伊勢神経懇話会

56回伊勢神経懇話会:2013522日(水)
症例報告:赤色骨髄(red bone marrow)の腰椎演者:宮崎眞佐男。座長:加藤保司。
使用文献:上谷雅孝. 腫瘍と誤りやすい病変と見落とされやすい病変. CLINICIAN. NO545,1219-1226,2005
症例報告:アパシー症候群の一例。演者:加藤保司。座長:小野直見。
使用文献:Levy R, Dubois B. Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cereb Cortex.                    2006;16:916-28.
症例報告:ありふれた血管性うつ状態演者:宮崎眞佐男。座長:加藤保司。
使用文献:Pan A,et al. Depression and Incident Stroke in Women. Stroke. 201;42:2770-5
講演「慢性期脳卒中・高次脳障害」演者:宮崎眞佐男。座長:加藤保司。
使用文献
Russ TC, et al. Association between psychological distress and mortality: individual participant pooled analysis of 10
prospective cohort studies. BMJ. 2012;345:e4933

Pan A, et al. Depression and incident stroke in women.Stroke. 2011;42:2770-5
Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache
Disorders; 2nd Edition. Cephalalgia 2004;24(suppl 1):1-160

國本 雅也:Syndromes of autonomic overactivity 自律神経過活動症候群.Brain Medical24:121-126,2012
Dudek FE. Microseizures in human neocortex: a role for ultra-small seizures? Epilepsy Curr. 2009;9:151-2
Kurth T,et al. Headache, migraine, and structural brain lesions and function: population based Epidemiology of
Vascular Ageing-MRI study. BMJ. 2011 Jan 18;342:c7357

Drachman DA, Hart CW. An approach to the dizzy patient. Neurology. 1972 Apr;22(4):323-34
Newman-Toker DE, et al. How often is dizziness from primary cardiovascular disease true vertigo?
A systematic review. J Gen Intern Med. 2008 Dec;23(12):2087-94

Yanik MF, et al. Neurosurgery: functional regeneration after laser axotomy. Nature. 2004;432:822
Molteni RF, et al. Voluntary exercise increases axonal regeneration from sensory neurons. Proc Natl Acad Sci U S A.
2004;101:8473-8

Ma DK, et al. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis.
Science. 2009;323:1074-7

Pan A,et al. Depression and Incident Stroke in Women. Stroke. 201;42:2770-5
Levy R, Dubois B. Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cereb Cortex. 2006;16:916-28
Howard G, et al. Stroke symptoms in individuals reporting no prior stroke or transient ischemic attack are associated with
a decrease in indices of mental and physical functioning. Stroke. 2007;38:2446-52

山本智子、宮崎眞佐男ら、認知症の視空間操作能力に対するGABA親和剤療法.神経内科70598-900,2009
中谷謙、宮崎眞佐男ら、ドパミン投与前後における失語症患者の音響分析. 神経内科70:580-584,2009
Yutaka Tanaka, Masao Miyazaki, Martin L Albert. Effects of increased cholinergic activity on naming in aphasia.
The Lancet 350:116-117,1997

55回伊勢神経懇話会:2013417 (水)
症例報告:海綿状血管腫の1演者:宮崎眞佐男。座長:加藤保司。使用文献:
徳永浩司、伊達勳:頭部に発生する海綿状血管腫および静脈性血管腫の臨床.BRAIN and NERVE 63:17-25, 2011        
 Sirvente J, Enjolras O, Wassef M, et al: Frequency and phenotypes of cutaneous vascular malformations in              
a consecutive series of 417 patients with familial cerebral cavernous malformations. J Eur Acad Dermatol Venereol.     
23:1066-1072, 2009脳卒中 治療ガイドライン20095-3.海綿状血管腫168-170
症例報告:てんかん部分発作による痴呆症様症状。演者:加藤保司。座長:小野直見。使用文献:
Olafsson E, et al. Incidence of unprovoked seizures and epilepsy in Iceland and assessment of the epilepsy          
syndrome classification: a prospective study. Lancet Neurol.2005;4:627-34 Forsgren L, et al. Incidence and clinical characterization of unprovoked seizures in adults: a prospective population-based study. Epilepsia.1996;37:224-9 Hauser WA, et al. Incidence of epilepsy
and unprovoked seizures in Rochester,
  Minnesota: 1935-1984. Epilepsia.1993;34:453-68 症例報告:左橋新鮮ラクネ梗塞・麻痺の見方。演者:宮崎眞佐男。座長:加藤保司。使用文献:
森本一至、宮崎眞佐男、津田光徳ら.腰 椎疾患におけるサ-モグラフィ-の有用性.医学検査431334-8,1994
Alter M. The digiti quinti sign of mild hemiparesis. Neurology 23: 503-505 ,1972
Ogawa Y, Sakakibara R. Platysma sign in high cervical lesion. J Neurol Neurosurg Psychiatry. 2005;76:735
講演「Generalistと脳卒中」演者:宮崎眞佐男。座長:加藤保司。
使用文献

 使用文献

Selwaness M,et al. Blood pressure parameters and carotid intraplaque hemorrhage as measured by magnetic   
resonance imaging: The Rotterdam Study. Hypertension. 2013;61:76-81 Lampl Y, et al. Minocycline treatment         in acute stroke: an open-label, evaluator-blinded study. Neurology. 2007;69:1404-10Hashioka S, et al.           Proton pump inhibitors exert anti-inflammatory effects and decrease human microglial and monocytic            THP-1 cell neurotoxicity. Exp Neurol.2009;217:177-83. EBMから見た脳卒中の治療 Clin.Neurusci 20:138-224.  
2002 Lindenauer PK,et al. Use of antihypertensive agents in the management of patients with acute ischemic stroke.     Neurology. 2004 ;63:318-23. Jamary Oliveira-Filho J,et al. Detrimental effect of blood pressure reduction in the first      24 hours of acute stroke onset. Neurology. 2003;61: 1047-51 Bernhardt J, et al. A very early rehabilitation trial        for stroke (AVERT): phase II safety and feasibility. Stroke. 2008;39:390-6 Mayo NE, et al. There's no place like       home : an evaluation of early supported discharge for stroke. Stroke.2000;31:2521-2 米国ガイドライン2006:       Stroke. 2006 Feb;37(2):577-617 the HYVET investigators. Incident dementia and blood pressure lowering           in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo     controlled trial. Lancet Neurol. 2008 Jul 7 Sabayan B, et al. High blood pressure and resilience to physical and      cognitive decline in the oldest old: the leiden 85-plus study. J Am Geriatr Soc. 2012;60:2014-9 Christensen K, et al.    Perceived age as clinically useful biomarker of ageing: cohort study. BMJ. 13 December 2009, doi:10.1136/bmj.b5262       JB, et al. Association between chlorthalidone treatment of systolic hypertension and long-term survival. JAMA. 2011 ;
306:2588-93
 Bybee KA, et al. Preoperative aspirin therapy is associated with improved postoperative        
outcomes in patients undergoing coronary artery bypass grafting. Circulation. 2005;112:I286-92  Agarwal S, et al. Current Trial-Associated Outcomes With Warfarin in Prevention of Stroke in Patients With    Nonvalvular Atrial Fibrillation: A Meta-analysis. Arch Intern Med. 2012;172:623-31 the ARISTOTLE Committees and Investigators. Apixaban versus Warfarin in Patients with Atrial Fibrillation. N Engl J Med 2011; 365 :981-92 Blanco M, et al. Statin treatment withdrawal in ischemic stroke: a controlled randomized study. Neurology. 2007;69:904-1 Milionis HJ, et al. Statin therapy after first stroke reduces 10-year stroke recurrence and improves survival. Neurology. 2009;72:1816-22  SPARCL Investigators. High-Dose Atorvastatin after Stroke or Transient Ischemic Attack.NEJM 355:549-559,2006 Haussen DC, et al.Statin Use and Microbleeds in Patients With Spontaneous Intracerebral Hemorrhage. Stroke. 2012;43:2677-81 21 American Heart Association Stroke Council, et al. Stroke. 2011 Jan;42:227-76 22    <!--[endif]-->the ExStroke Pilot Trial Group.ExStroke Pilot Trial of the effect of repeated instructions to improve physical activity after ischaemic stroke: a multinational randomised controlled clinical trial. Circulation. BMJ 2009;339:b2810. 23    <!--[endif]-->Zheng W, et al. Association between Body-Mass Index and Risk of Death in More Than 1 Million Asians. N Engl J Med. 2011; 364 : 719 – 29 24Silventoinen K, et al.Does obesity modify the effect of blood pressure on the risk of cardiovascular disease? A population-based cohort study of more than one million Swedish men. Circulation. 2008;118:1637-42  Agarwal S, et al. Current Trial-Associated Outcomes With Warfarin in Prevention of Stroke in Patients With  Nonvalvular Atrial Fibrillation: A Meta-analysis. Arch Intern Med. 2012;172:623-31 the ARISTOTLE Committees and Investigators. Apixaban versus Warfarin in Patients with Atrial Fibrillation. N Engl J Med 2011; 365 :981-92 Blanco M, et al. Statin treatment withdrawal in ischemic stroke: a controlled randomized study. Neurology. 2007;69:904-1 Milionis HJ, et al. Statin therapy after first stroke reduces 10-year stroke recurrence and improves survival. Neurology. 2009;72:1816-22   
SPARCL Investigators. High-Dose Atorvastatin after Stroke or Transient Ischemic Attack.NEJM 355:549-559,2006     
Haussen DC, et al.Statin Use and Microbleeds in Patients With Spontaneous Intracerebral Hemorrhage. Stroke. 2012;43:2677-81 21 American Heart Association Stroke Council, et al. Stroke. 2011 Jan;42:227-76 22    <!--[endif]-->the ExStroke Pilot Trial Group.ExStroke Pilot Trial of the effect of repeated instructions to improve physical activity after ischaemic stroke: a multinational randomised controlled clinical trial. Circulation. BMJ 2009;339:b2810. 23    <!--[endif]-->Zheng W, et al. Association between Body-Mass Index and Risk of Death in More Than 1 Million Asians. N Engl J Med. 2011; 364 : 719 – 29 24Silventoinen K, et al.Does obesity modify the effect of blood pressure on the risk of cardiovascular disease? A population-based cohort study of more than one million Swedish men. Circulation. 2008;118:1637-42 

54回伊勢神経懇話会:2013327 (水)
症例報告:アルコール性振戦?本態性振戦?と振戦図演者: 宮崎眞佐男。座長:加藤保司。
使用文献:
村井克 , 宮崎眞佐男ら,:本態性振戦のMR神経路 画像. 神経内 科 46535538,1997
Higgins JJet al.A variant in the HS1-BP3 gene is associated with familial essential tremor. Neurology. 2005 8;64(3):417-21
Pinto AD, et al.: The celebellothalamocortical pathway in essential tremor. Neurology.2003 24;60(12):1985-7
Zesiewicz TA. et al & : Practice parameter: therapies for essential tremor: report of the Quality Standards Subcommittee of the
American Academy of Neurology. Neurology 2005 28;64(12):2008-20.

症例報告:Hysteric monoparesisとアクチグラフィー。演者:加藤保司。座長:小野直 見。使用文献:①神内45:351-354,1996②神経治療学15:301-308,1998③神内54:551-556,2001 ④自律神経40:30-35,2003.Psychiatry Clin Neurosci. 2002 ;56:221-2.Psychiatr Pol. 2004 ;38:1127-43
症例報告:1ヶ月で消失した慢性硬膜下血腫演者:宮崎眞佐男。座長:加藤保司。
使用文献:宮崎真 佐男、竹内藤吉、和賀志郎ら.髄液細胞増多を伴い、慢性硬膜下血腫内に再出血のみられた1例.最新医学35213521371980山本  隆充:保存的治療を行ったthin acute subdural hematomaにおける自然治癒例と慢性硬膜下血腫移行例との比較検討、日本脳神経外 科学会46回総会抄録集1901987 
講演 「せん妄について」演者:宮崎眞佐男。座長:加藤保司。
使用文献
Ely EW, et al.Delirium in mechanically ventilated patientsvalidity and reliability of the confusion assessment method for the intensive care unit(CAM-ICU).JAMA 20012862703-2710
laschke K, et al.Comparison of the confusion assessment method for the intensive care unitCAM-ICUwith the Intensive Care Delirium Screening ChecklistICDSCfor delirium in critical care patients gives high agreement rate(s) Intensive Care Med200834431-436
Pandharipande P, et al.Motoric subtypes of delirium in mechanically ventilated surgical and trauma intensive care unit patients. Intensive Care Med 2007331726-1731
Gunther ML, et al : Pathophysiology of delirium in the intensive care unit.Crit Care Clin2008;24:45-65
Devlin JW, et al.Delirium assessment in the critically ill.Intensive Care Med 200733929-940.
Pandharipande P, et alDeliriumacute    cognitive dysfunction in the critically ill. Curr Opin Crit Care200511360-368
Choi SH, et al. Neural network functional  connectivity during and after an episode of delirium. Am J Psychiatry. 2012;169:498-507
Thomas C, et al.Diagnosing delirium in older hospitalized adults with dementia: adapting the confusion assessment method to international classification of diseases, tenth revision, diagnostic criteria. J Am Geriatr Soc. 2012;60:1471-7
Breitbart Wet alA doubleblind trial of haloperidolchlorpromazineand lorazepam in the treatment of delirium in hospitalized AIDS patientsAm J Psychiatry 1532317,1996
DART-AD investigators. The dementia antipsychotic withdrawal trial (DART-AD): long-term follow-up of a randomised placebo-controlled trial. Lancet Neurol. 2009 ;8:151-7
De Deyn PP, et al. Aripiprazole in the treatment of Alzheimer's disease. Expert Opin Pharmacother. 2013 Jan 28
Ely EW, et al.Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit.JAMA 20042911753-1762
Fong TG, et al. Adverse outcomes after hospitalization and delirium in persons with Alzheimer disease. Ann Intern Med. 2012;156:848-56
Shi Q, et al. Delirium in acute stroke: a systematic review and meta-analysis. Stroke. 2012;43:645-9
Guideline Development Group. Synopsis of the National Institute for Health and Clinical Excellence guideline for prevention of delirium. Ann Intern Med. 2011;154:746-51
Inouye SK, et al. Risk factors for delirium at discharge: development and validation of a predictive model. Arch Intern Med. 2007;167:1406-13

53回伊勢神経懇話会:2013220日(水)
症例報告:ベルガ腔から精神症状を呈した1例。演者:宮崎眞佐男。座長:加藤保司。
使用文献:
①宮永和夫ら.精神医学2743-491985.②厚生省精神・神経疾患研究7年度研究報告書 Page171-178,1996.03
Wang KC, et al.Cephalalgia. 2004;24:867-74.日本眼科学会雑誌94537-543
症例報告:自律神経炎からAllodynia(異痛症)を起こした1。演者:加藤保司。座長:小野直見。
使用文献
Miraucourt LS, et al. J Neurosci. 2009 Feb 25;29(8):2519-27②植田弘師、日本薬理学雑誌127:2006;161-165
症例報告:マイオジール(脊髄造影剤)による脳幹化学的炎症の1
演者:宮崎眞佐男。座長:加藤保司。使用文献:
①筒井 求ら, 油性造影剤による遅発性脊髄症の1.整形外科52:661-664,2001
講演「痛みの機序と私の治療」演者:宮崎眞佐男。座長:加藤保司。
使用文献
Ardid D, et al. Involvement of bulbospinal pathways in the antinociceptive effect of clomipramine in the rat. Brain Res
1995;695:253-256

Miraucourt LS, et al. J Neurosci. 2009 Feb 25;29(8):2519-27
Wang XL, Zhang HM, Chen SR, Pan HL. Altered synaptic input and GABAB receptor function in spinal superficial dorsal
horn neurons in rats with diabetic neuropathy. J Physiol 2007;579(Pt 3):849-861.

Sung B, Lim G, Mao J. Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats. J Neurosci 2003;23(7):2899-2910.
Halassa MM, Fellin T, Haydon PG. The tripartite synapse: roles for gliotransmission in health and disease.
Trends Mol Med 2007;13(2):54-63.

Milligan ED, Watkins LR. Pathological and protective roles of glia in chronic pain. Nat Rev Neurosci 2009;10(1):23-36.
村井克昌, 宮崎眞佐男ら、Parkinson病の冷刺激による痛覚認知時間の延長について。神経内科.6379-822005
加藤総夫.慢性痛における扁桃体シナプス伝達の可塑的変化.医学のあゆみ223:706-7122007.
日本医師会.日本医師会雑誌特別号 第119巻第12号。痩痛コントロールABC1998
May A. Chronic pain may change the structure of the brain. Pain. 2008 Jul;137(1):7-15.
Singer T, et al. Empathy for pain involves the affective but not sensory components of pain. Science. 2004;303:1157-62.
Eisenberger NI,et al. Does rejection hurt? An FMRI study of social exclusion. Science. 2003;302:290-2.
林田眞和他. 末梢性神経因性疼痛における薬理学的疼痛機序判別試験(DCT)の結果とその臨床的意義:
オピオイド研究の進歩と展望
.ネオメディカル社,2004
南雅文、佐藤公道.『痛み』による『負の情動反応』における扁桃体の役割.日本薬理学雑誌 125:5-9,2005.
Knabl J, et al.Reversal of pathological pain through specific spinal GABAA receptor subtypes.Nature. 2008 Jan 17;451(7176):330-4.
Stahl SM.Independent actions on fear circuits may lead to therapeutic synergy for anxiety when combining serotonergic and
GABAergic agents.J Clin Psychiatry. 2002 Oct;63(10):854-5.

Strigo IA, et al.Association of major depressive disorder with altered functional brain response during anticipation and
processing of heat pain.Arch Gen Psychiatry. 2008 Nov;65(11):1275-84.

Jann MW, Slade JH. Antidepressant agents for the treatment of chronic pain and depression. Pharmacotherapy.
2007 Nov;27(11):1571-87

Paulus MP, et al. Dose-dependent decrease of activation in bilateral amygdala and insula by lorazepam during emotion processing.
Arch Gen Psychiatry. 2005 Mar;62(3):282-8.

Shin LM, et al. A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly
presented fearful faces in posttraumatic stress disorder. Arch Gen Psychiatry. 2005 Mar;62(3):273-81

52回伊勢神経懇話会:2013123日(水)
症例報告:これが脳梗塞?視床ラクネ梗塞の1演者:宮崎眞佐男。座長:加藤保司。
使用文献:

①川田、宮崎ら.右視床梗塞により一過性の人形現象を呈した
1.臨床神経42:922-924,2002.Bogoousslavsky J, et al.
Thalamic infarcts: clinical syndromes, etiology and prognosis.Neurology38:837-848,1988.
Schmahmann JD.
Vascular syndromes of the thalamus. Stroke34:2264-2278,2003.
Bassetti C, et al. Hypersomnia following paramedian
thalamic stroke : a report of 12 patients. Ann Neurol39:471-480,1996.
⑤織田雅也ら. 両側視床傍正中部梗塞症候群.
神経内科
60:10-15,2004
症例報告:TIA?脳梗塞?の1例。演者:加藤保司。座長:小野直見。使用文献:
EBMから見た脳卒中の治療Clin.Neurusci 20:138-224.2002
症例報告:血管性舞踏病の1演者:宮崎眞佐男。座長:加藤保司。使用文献:
①脳と神経58:155-159,2006。②Internal Medicine44:1280-1285,2005。③臨床神経学45:502-505,2005
④神経内科
61:454-458,2004。⑤臨床神経学44:365-368,2004。⑥内科97:618-621,2006。⑦Brain & Development27:62-65,2005
症例報告:RAにおける脳血管障害。演者:加藤保司。座長:小野直見。使用文献:
Nadareishvili Z, et al.Cardiovascular, rheumatologic, and pharmacologic predictors of stroke in patients with rheumatoid arthritis:
a nested, case-control study. Arthritis Rheum. 2008;59:1090-6.

Aviña-Zubieta JA, et al. Risk of cardiovascular mortality in patients with rheumatoid arthritis:
A meta-analysis of observational studies. Arthritis Rheum. 2008 ;59:1690-7

講演「2012年印象に残った臨床例と薬剤-手指変形性関節症・Dupuytren拘縮・de Quervain腱鞘炎・
緊張型筋炎
(tension myositis)・睡眠関連摂食障害及びアスピリン・セルベックス・セルシン」
演者:宮崎眞佐男。座長:加藤保司。
使用文献
KozmaEwa Maria et al. The Journal of Biochemistry137:463-476,2005
Meyerding HW:Dupuytren's contracture.Arch Surg 32:320-323,1936.
亀山真ら.糖尿病に伴う狭窄性屈筋腱腱鞘炎の臨床的病態.整形外科62401-4042011
Sarno JE. Etiology of neck and back pain. J Nerv Ment Dis.1981;169:55-9
Nirenberg MJ, Waters C. Nocturnal eating in restless legs syndrome. Mov Disord. 2010 Jan 15;25(1):126-7.
Vetrugno R, et al. Nocturnal eating: sleep-related eating disorder or night eating syndrome? A videopolysomnographic study. 
Sleep. 2006 Jul 1;29(7):949-54.

Martinez-Salio A, et al. Nocturnal sleep-related eating disorder that responds to topiramate. Rev Neurol. 2007 Sep 1-15;45(5):276-9.
Provini F, et al. Increased prevalence of nocturnal smoking in restless legs syndrome (RLS). Sleep Med. 2010 Feb;11(2):218-20.
Ridker PM, et al. A Randomized Trial of Low-Dose Aspirin in the Primary Prevention of Cardiovascular Disease in Women.
N Engl J Med. 2005;35:1293-304

Rothwell PM, et al. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five
randomised trials. Lancet. 2010;376:1741-50

Rothwell PM, et al. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data
from randomised trials. Lancet. 2011;377:31-41

Singer E, et al . Effect of Aspirin Versus Clopidogrel on Walking Exercise Performance in Intermittent Claudication: A Double-Blind Randomized Multicenter Trial. J Am Heart Assoc 2012;1:51-55
The SPS3 Investigators. Effects of Clopidogrel Added to Aspirin in Patients with Recent Lacunar Stroke.
N Engl J Med 2012;367:817-825

Bybee KA, et al. Preoperative aspirin therapy is associated with improved postoperative outcomes in patients
undergoing coronary artery bypass grafting. Circulation. 2005;112:I286-92

Manocha D, et al. Bleeding Risk after Invasive Procedures in Aspirin/NSAID Users: Polypectomy Study in Veterans. Am J Med. 2012;125:1222-7
Maulaz AB, et al. Effect of discontinuing aspirin therapy on the risk of brain ischemic stroke. Arch Neurol. 2005;62:1217-20
Hirakawa, T, et al.:Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and
rat gastric mucosa. Gastroenterology, 111, 345
357,1996
Sinn DI, et al. Pharmacological induction of heat shock protein exerts neuroprotective effects in experimental
intracerebral hemorrhage. Brain Res. 2007;1135:167-76

de Gage SB,et al. Benzodiazepine use and risk of dementia: prospective population based study.
BMJ 2012; 345 doi: 10.1136/bmj.e6231

Russ TC, et al. Association between psychological distress and mortality: individual participant pooled analysis of
10 prospective cohort studies. BMJ. 2012 Jul 31;345:e4933. doi: 10.1136/bmj.e4933

21 Egido JA, et al. Is psycho-physical stress a risk factor for stroke? A case-control study. J Neurol Neurosurg Psychiatry.
2012;83:1104-10

22  Inomata S, et al. CYP2C19 genotype affects diazepam pharmacokinetics and emergence from general anesthesia.
Clin Pharmacol Ther. 2005;78:647-55

23  Grower MF, Russell EA Jr, Getter L. Solubility of injectable Valium in intravenous solutions. Anesth Prog. 1978 Sep-Oct;25(5):158-60

51回伊勢神経懇話会:20121121日(水)
 症例報告:顎下腺腫瘍で難聴を来たし、音楽性幻聴を伴う1
演 者:宮崎眞佐男。座長:加藤保司。使用文献:

熱田英範ら.精 神科10:518-523,2007. Hubl D,  et al. Arch Gen Psychiatry. 2004;61:658-68.
③山本雅清ら、分子精神医学
485-862004④ 向井栄一郎、神経内科53:516-522,2000
MIMI H. KAO, et al Nature2005:433,638-643.⑥ 姉川孝神経内科53:528-534,2000
 症例報告:Empty Sella症候群の1例。 演者:加藤保司。座長:小野直見。使用文献:
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Agarwal JK et al.Empty sella syndrome. Journal, Indian Academy of Clinical Medicine 2:198-202,2001
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Neelon FA, Goree JA, Lebovitz HE. The primary empty sella: clinical and radiographic characteristics and endocrine functions.
Medicine 1973; 52: 73-92.
⑤駒津光久.Primary empty sella syndrome(PESS)における抗下垂体細胞膜抗体(PCSA)の 検討.
信州医学雑誌
38:77-88,1990⑥村岡章弘ら.急性脳脊髄膜炎を契機にempty sella症候群および汎下垂体機能低下症をきたした1例.
日内会誌
78: 684685, 1989Murat S, et al. Clinical Report of 28 Patients with Sheehan's Syndrome. Endocrine Journal
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Pocecco M, De Campo O, Marinoni S et al. High frequency of empty sella syndrome in children with growth
hormone deficiency. Helv Paediatr Acta 1989;43: 295-301.

 症例報告:不思議の国アリス症候群の1演 者:下村 有利那。座長:加藤保司。使用文献:
Cinbis M, Aysun S. Alice in Wonderland syndrome as an initial manifestation of Epstein-Barr virus infection.
Br J Ophthalmol. 1992;76:316

②Mizuno M, et al. 'Alice in Wonderland' syndrome as a precursor of depressive disorder. Psychopathology. 1998;31:85-9
Brumm K,  et al. Functional magnetic resonance imaging of a child with Alice in Wonderland syndrome
during an episode of micropsia. J AAPOS. 2010;14:317-22

Binalsheikh IM, et al. Lyme neuroborreliosis presenting as Alice in Wonderland syndrome. Pediatr Neurol. 2012;46:185-6
山根清美.片頭痛と不思議の国アリス症候群.Medical Practice20:1031-1033,200
Nakaya H et al. Alice in Wonderland syndrome caused by the 2009 pandemic H1N1 influenza A virus. Pediatr Infect Dis J.
2011;30:725-6

 講演「不眠症について」演者:宮崎眞佐男。座長:加藤保司。使用文献:
櫻井武. 睡眠の科学―なぜ眠るのかなぜ目覚めるのか- ブ ルーバックス
Del Valle J, Gantz I. Novel insights into histamine H2 receptor biology. Am J Physiol 1997; 273: G987-996
Nishino S, et al. Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to
healthy controls. Sleep. 2009;32:175-80.

福井裕行.医 学のあゆみ187:11-17,1998
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Stahl SM. Psychopharmacology of wakefulness: pathways and neurotransmitters.  J Clin Psychiatry. 2002 Jun;63(7):551-2.
Gould KS et al, Effects of 60 hours of total sleep deprivation on two methods of high-speed ship navigation. Ergonomics.
2009;52:1469-86

(Doghramji K, et al. A normative study of the maintenance of wakefulness test (MWT). Electroencephalogr Clin Neurophysiol.
1997;103:554-62

Huber R, et al. Local sleep and learning. Nature. 2004 Jul 1;430(6995):78-81
Vyazovskiy VV, et al. Local sleep in awake rats. Nature. 2011;472:443-7
Roffwarg HP, Muzio JN : Ontogenic development of the human sleepdream cycle; the prime role of dreaming sleep in early
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Aton SJ, et al. Mechanisms of sleep-dependent consolidation of cortical plasticity. Neuron. 2009;61:454-66
Gais S, Born J. Low acetylcholine during slow-wave sleep is critical for declarative memory consolidation. Proc Natl Acad Sci U S A. 2004;101:2140-4
Peigneux P, et al. Are spatial memories strengthened in the human hippocampus during slow wave sleep? Neuron. 2004;44:535-45
Kasukawa T, et al. Human blood metabolite timetable indicates internal body time. Proc Natl Acad Sci U S A. 2012;109:15036-41
Bessho Y, et al.Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock. Genes Dev. 2003;17:1451-6
田ヶ 谷浩邦.概日リズム睡眠障害.日本臨牀67:1501-1506, 2009

50回伊勢神経懇話会:20121024日(水)
例報告:上肢単麻痺を呈した脳梗塞-pre-central knobについて-
演者:宮崎眞佐男。座長:村井 克昌。使用文献:
高宮孝悟ら.下垂手を主訴とする脳梗塞の一例.臨床神経学29:778-780,1989
後藤俊臣ら.中大脳動脈分枝解離による脳梗塞の1例. 臨床神経学36 : 312-317,1996
中洲庸子ら.MRI て障害部位を明瞭に描出しえた下垂手を主訴とする脳梗塞の1例.
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柿沼佳渚子ら、偽性尺骨神経麻痺で発症した内頸動脈狭窄にともなう
進行性脳梗塞臨床神経2010;50:666-668
太田聡ら、Unilateral monoataxia
呈した中心前・後回小梗塞の2症例.脳と神経57:1083-10872005
Yousry TA, et al. Localization of the motor hand area to a knob on the precentral gyrus.
A new landmark. Brain 120 : 141-57, 1997

例報告:家族性低セルロプラスミン血症と思われる1例。演者:加藤保司。座長:小野直見。
使 用文献:
宮嶋裕明. セル ロプラスミン異常と鉄過剰症. 血液フロンティア10:1279-1287,2000
藤木僚.他. 統合 失調症様症状が出現した家族性低セルロプラスミン血症の1. 精神科16:180-185,2010
四茂野はるみら.セル ロプラスミン遺伝子変異をヘテロでともなった多系統萎縮症の1剖検例.
臨床神経
43398402,2003
木村暁夫ら.分裂病様 精神症状で初発し,血清鉄低値,低セルロプラスミン血 ,網膜電図異常を呈した
小脳変性症の1例 新しい症候群?臨床神経学41:507-511,2001
藤木僚.他. 統合 失調症様症状が出現した家族性低セルロプラスミン血症の1. 精神科16:180-185,2010
四茂野はるみら.セル ロプラスミン遺伝子変異をヘテロでともなった多系統萎縮症の1剖検例.
臨床神経
43398402,2003
例報告:失書から始まった緩徐進行性失語(前頭-側頭型認知症)1例。演者:下村 有利那。
座長:加藤保司。使用文献:

井知代子,岩田誠,緩徐進行性失語の書字障害.臨床神経学,4384-92,2003
Mackenzie IRA, , et al. Acta Neuropathol 119:1-4, 2010.
吉村教暤、弘前医療福祉大学11 22, 2009
演「老人の歩行障害について」演者:宮崎眞佐男。座長:加藤保司。
使用文献
Kritchevsky SB, et al. Angiotensin-converting enzyme insertion/deletion genotype, exercise, and physical decline.
JAMA. 2005;294:691-8

LADIS Study Group. Association of gait and balance disorders with age-related white matter changes: the LADIS study.
Neurology. 2008;70:935-42

Wang L, et al. Performance-based physical function and future dementia in older people. Arch Intern Med.
2006;166:1115-20

Suzuki M, et al. Impact of fall-related behaviors as risk factors for falls among the elderly patients with
dementia in a geriatric facility in Japan. Am J Alzheimers Dis Other Demen. 2012;27:439-46

渡辺栄一.変性腰椎側弯の臨床的検討、福島医誌39:487-495,1989
菊地臣一.腰椎背筋群におけるコンパートメント症候群の病態と治療、
リハビリテーション医学
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Evans WJ, et al. Cachexia: a new definition. Clin Nutr. 2008;27: 793-9
You SH, et al. Virtual reality-induced cortical reorganization and associated locomotor recovery in chronic stroke:
an experimenter-blind randomized study.  Stroke. 2005;36:1166-71

Agrawal Y, et al. Disorders of balance and vestibular function in US adults: data from the National Health and
Nutrition Examination Survey, 2001-2004.  Arch Intern Med. 2009;169:938-44

49回伊勢神経懇話会2012919日(水)
症例報告:偽性副甲状腺機能低下症の1例。演者:宮崎眞佐男。座長:加藤保司。
使用文献:
Clinical Calcium17 :1214-1219,2007Clinical Pediatric Endocrinology16:31-36,2007
Endocrine Journal55:169-173,2008Clinical Pediatric Endocrinology20:21-23,2011
Clinical Calcium17:1222-1227,2007
症例報告:結節性硬化症の1例。演者:加藤保司。座長:小野直見。
使用文献:
Nature. 2007;445:785-8. Nat Med. 2008 Aug;14(8):843-8.N Engl J Med 2010; 363 : 1801-11
N Engl J Med. 2008;358:140-51. Hope Northrup , MD, FACMG; Kit-Sing Au, PhD..GeneReview
症例報告:髄液細胞の正常なウィルス性髄膜炎と考えられる1例。演者:宮崎眞佐男。
座長:加藤保司。
使用文献:

国立予防衛生研究所、厚生省結核感染症課.無菌性髄膜炎.病原微生物検出情報18:127-
128,1997
・エコー30型による無菌性髄膜炎の流行. 病原微生物検出情報4:44-45,1983・無菌性
髄膜炎関連エンテロウイルスの動向
19992002. 病原微生物検出情報23:193-194,2002
Cherry JD and Shields WD. Aseptic meningitis and viral meningitis. In Textbook of Pediatirc
infectious diseases 4th Ed., Saunders, Philaderphia, 457
467,1998
Attia J, et al. The rational clinical examination. Does this adult patient have acute meningitis? JAMA1999;282:175-81
Uchihara T, Tsukagoshi H. Jolt accentuation of headache: the most sensitive sign of CSF pleocytosis.
Headache. 1991;31:167-71.
小児科臨床46:1231-1238,1993
日本小児科学会雑誌97:953-958,1993
講演「サプリメント・磁気・飲料の功罪」演者:宮崎眞佐男。座長:加藤保司。
使用文献
1) Hu EA, et al. White rice consumption and risk of type 2 diabetes: meta-analysis and systematic review.
BMJ.2012;344:e1454
2)
村井克昌、宮崎真佐男ら、胃切除後、経静脈栄養下で発症したWernick脳症の1例.神経内科43:65-68,1995
3)Heart Outcomes Prevention Evaluation (HOPE) 2 Investigators. Homocysteine lowering with folic
acid and B vitamins in vascular disease. N Engl J Med. 2006;354:1567-77
4)NORVIT Trial Investigators. Homocysteine lowering and cardiovascular events after acute myocardial
infarction. N Engl J Med. 2006;354:1578-88.
5)Vogiatzoglou A, et al. Vitamin B12 status and rate of brain volume loss in community-dwelling elderly.
Neurology. 2008;71:826-32
6)Aisen PS, et al; Alzheimer Disease Cooperative Study. High-dose B vitamin supplementation and cognitive
decline in Alzheimer disease: a randomized controlled trial. JAMA. 2008;300:1774-83
7)Myint PK, et al. Combined effect of health behaviours and risk of first ever stroke in 20,040 men and women
over 11 years' follow-up in Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk):
prospective population study. BMJ. 2009 Feb 19;338:b349. doi
8)Gaziano JM, et al. Vitamins E and C in the Prevention of Prostate and Total Cancer in Men: The Physicians'
Health Study II Randomized Controlled Trial. JAMA. 2009;301:52-62
9)Galasko DR, et al; for the Alzheimer's Disease Cooperative Study. Antioxidants for Alzheimer
Disease: A Randomized Clinical Trial With Cerebrospinal Fluid Biomarker Measures. Arch Neurol. 2012 Mar 19
10)Sch?rks M, et al. Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials.
BMJ. 2010 Nov 4;341:c5702
11)Kang JH, et al. A randomized trial of vitamin E supplementation and cognitive function in women.
Arch Intern Med. 2006;166:2462-8
12)Petersen RC, et al & ; Alzheimer's Disease Cooperative Study Group. Vitamin E and Donepezil for the
Treatment of Mild Cognitive Impairment. N Engl J Med 2005;352:2379-88
13)Galasko DR, et al; for the Alzheimer's Disease Cooperative Study. Antioxidants for Alzheimer Disease: A
Randomized Clinical Trial With Cerebrospinal Fluid Biomarker Measures. Arch Neurol. 2012 Mar 19
14)Fujita K, et al. Vitamin E decreases bone mass by stimulating osteoclast fusion. Nat Med. 2012;18:589-94
15)Bolland MJ, et al. Vascular events in healthy older women receiving calcium supplementation: randomised
controlled trial. BMJ. 2008;336:262-6
16)DIPART (Vitamin D Individual Patient Analysis of Randomized Trials) Group. Patient level pooled analysis
of 68 500 patients from seven major vitamin D fracture trials in US and Europe. BMJ. 2010 Jan 12;340:b5463
17)Bischoff-Ferrari HA, et al. A pooled analysis of vitamin D dose requirements for fracture prevention.
N Engl J Med 2012; 367:40-49
18)Munger KL, et al. Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA. 2006 Dec
20;296 (23):2832-8
19)Wandel S, et al. Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or
knee: network meta-analysis. BMJ. 2010 Sep 16;341:c4675
20)Pittler MH, et al  Static magnets for reducing pain: systematic review and meta-analysis of randomized trials.
CMAJ. 2007;177:736-42
21)Liang W, et al. Tea consumption and ischemic stroke risk: a case-control study in southern China. Stroke.
2009 Jul;40:2480-5
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causes in Japan: the Ohsaki study. JAMA. 2006;296:1255-65
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24)Silletta MG, et al ; GISSI-Prevenzione Investigators. Coffee consumption and risk of cardiovascular events
after acute myocardial infarction: results from the GISSI (Gruppo Italiano per lo Studio della Sopravvivenza
nell'Infarto miocardico)-Prevenzione trial. Circulation. 2007;116:2944-51

48回伊勢神経懇話会2012718日(水)
症例報告:無症候性髄膜腫の1例。演者:宮崎眞佐男。座長:加藤保司。使用文献:
The Kumamoto brain tumor research group. Indications for surgery in patients with
asymptomatic meningiomas based on an extensive experience. J Neurosurg 2006; 105: 538-543.
症例報告:アミロイドアンギオパチーの1例。演者:加藤保司。座長:小野直見。使用文献:
浜口 毅 山田 正仁 脳と神経601275-12832008
Pezzini A, Del Zotto E, Volonghi I, Giossi A, Costa P, Padovani A. Cerebral amyloid angiopathy
: a common cause of cerebral hemorrhage. Curr Med Chem. 2009;16(20):2498-513.
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Amyloid Angiopathy Documented by 99mTc-ECD Brain Perfusion SPECT. J Nucl Med. Dec 2009;
50(12):1969-74.
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amyloid angiopathy. Neurology. Feb 10 2004;62(3):494-7.
Cano LM, Martinez-Yelamos S, Majos C, Alberti MA, Boluda S, Velasco R, et al. Reversible acute
leukoencephalopathy as a form of presentation in cerebral amyloid angiopathy. J Neurol Sci. Oct 2
2 2009;
Greenberg SM. Cerebral amyloid angiopathy: prospects for clinical diagnosis and treatment.
Neurology. Sep 1998;51(3):690-4..
Yamashita T, Ando Y, Ueda M, Nakamura M, Okamoto S, Zeledon ME. Effect of liver transplantation
on transthyretin Tyr114
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吉田光宏, 山田正仁.脳血管疾患の診断の最前線 脳アミロイドアンギオパチー 病態と診断法の進歩.
医学のあゆみ
231445-4512009
症例報告:ダウン症候群の中枢神経病変。演者:宮崎眞佐男。座長:加藤保司。使用文献:
Huether CA, et al. Maternal age specific risk rate estimates for Down syndrome among live births in
whites and other races from Ohio and metropolitan Atlanta, 1970-1989. J Med Genet. 1998;35:482-90..

日本小児循環器学会雑誌
26:256-266,2010.
Congenital Anomalies45: 62-64,2005.Pediatrics International53:72-77,2011.
信州医学雑誌 45:193-206,1997.脳と発達19:309-314,1987.Arron JR, et al. NFAT dysregulation
by increased dosage of DSCR1 and DYRK1A on chromosome 21. Nature. 2006 Jun 1;441:595-600

Sun X, He G, Song W. BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis
of Alzheimer's disease in Down syndrome. FASEB J. 2006 Jul;20:1369-76
講演「運動療法-老化・免疫・代謝、及び各種疾患についてー」演者:宮崎眞佐男。座長:加藤保司。
使用文献
1)
井出利憲. 細胞老化:細胞老化は個体老化の原因である. 医学のあゆみ217:757-762,2006
2)Fitzpatrick, AL et al. Leukocyte telomere length and cardiovascular disease in the cardiovascular
health study. Am. J. Epidemiol. 2007; 165:14
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3)Ruthenburg AJ, et al. Multivalent engagement of chromatin modifications by linked binding modules.
Nat Rev Mol Cell Biol 2007
8983-994. 
4)Outeiro TF, et al. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of
Parkinson's disease. Science. 2007;317:516-9
5)Cherkas LF, et al. The association between physical activity in leisure time and leukocyte
telomere length. Arch Intern Med. 2008;168:154-8
6)Wen CP, et al. Minimum amount of physical activity for reduced mortality and extended life
expectancy: a prospective cohort study. Lancet 2011;378:1244-53
7)Hegde SV, et al. Effect of 3-month yoga on oxidative stress in type 2 diabetes with or without
complications: a controlled clinical trial. Diabetes Care. 2011;34:2208-10
8)Slentz CA, et al. Inactivity, exercise training and detraining, and plasma lipoproteins. STRRIDE:
a randomized, controlled study of exercise intensity and amount. J Appl Physiol. 2007;103:432-42
9)Smith TP, et al. Influence of age and physical activity on the primary in vivo antibody and T
cell-mediated responses in men. Journal of Applied Physiology 2004;97: 491-498
10)Chubak J, et al. Moderate-intensity exercise reduces the incidence of colds among postmenopausal
women.Am J Med. 2006;119:937-42
11)Hu G, et al. Leisure time, occupational, and commuting physical activity and the risk of stroke.
Stroke. 2005;36:1994-9
12)Fitzpatrick AL, et al. Leukocyte telomere length and cardiovascular disease in the cardiovascular
health study. Am J Epidemiol. 2007;165:14-21
13)Geda YE, et al. Physical exercise, aging, and mild cognitive impairment: a population-based study.
Arch Neurol. 2010;67:80-6
14)Baker LD, et al. Effects of aerobic exercise on mild cognitive impairment: a controlled trial.
Arch Neurol. 2010;67:71-9
15)Stewart KJ, et al. Exercise effects on bone mineral density relationships to changes in fitness
and fatness. Am J Prev Med. 2005;28(5):453-60
16)Dunn AL, et al. Exercise treatment for depression: efficacy and dose response. Am J Prev Med.
2005;28:1-8
17)Chalder M, et al. Facilitated physical activity as a treatment for depressed adults: randomised
controlled trial. BMJ. 2012 Jun 6;344:e2758
講演「熱中症について」演者:宮崎眞佐男。座長:加藤保司。
 使用文献
 日本救急医学会 熱中症に関する委員. 会本邦における熱中症の現状? Heatstroke STUDY2010最終報告?
日救急医会誌.
2012; 23: 211-30
三宅康史ら、熱中症の実態調査- Heatstroke STUDY 2006 最終報告-日救急医学会誌2008;19:309-
21
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Exp Pharmaco
l Physiol 26:826.99,Cirt Rev Immunol 19:285.99

47回伊勢神経懇話会:2012627日(水)
症例報告:アレルギー性口内炎の1演者:宮崎眞佐男。座長:加藤保司。使用文献:
 1) 宮崎正 監修:口腔外科学-第2版:医歯薬出版株式会社、2005  
 2) 南雲正男 編著:口内炎、口腔乾燥症の正しい口腔ケア:医薬ジャーナル社、2001 
 3) 山根源之 編著:日本歯科評論 増刊チェアーサイドで活用する最新口腔粘膜疾患の診かた:(株)ヒョーロン、2007
 4) 佐々木忠昭・今井裕 編:歯科医療 2004年秋号(Vol.18 No.4)「最新の歯科免疫学-口腔病変と免疫のしくみ」,第一歯科出版
 5) 日本歯科医師会, 静岡県歯科医師会:EBMに基づいた口腔ケアのために―必読文献集,医歯薬出版 2002
症例報告:Failed neck & back surgery syndrome1例。演者:加藤保司。座長:小野直見。文献:
    Hubert L. Rosomoff: 17回米国疼痛学会. 2001
    Pearce JM. Aspects of the failed back syndrome: role of litigation. Spinal Cord. 2000;38:63-70.
    JAMA. 2006 22;296:2441-50
     Slipman CW, et al.Etiologies of failed back surgery syndrome. Pain Med. 2002;3:200-14
症例報告:傍腫瘍性?ウィルス性?嗅覚障害の1演者:宮崎眞佐男。座長:加藤保司。
 使用文献:

     Seo BS, et al. Treatment of postviral olfactory loss with glucocorticoids, Ginkgo biloba, and mometasone nasal spray.
      Arch Otolaryngol Head Neck Surg. 2009 Oct;135(10):1000-4.

  ② Ross GW, et al. Association of olfactory dysfunction with risk for future Parkinson's disease. Ann Neurol. 2008 Feb;63(2):167-73.
講演「腰痛診断・治療について」演者:宮崎眞佐男。座長:加藤保司。
 使用文献
     加藤総夫.慢性痛における扁桃体シナプス伝達の可塑的変化.医学のあゆみ223:706-7122007
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      On behalf of the COST B13 Working Group on Guidelines for Chronic Low Back Pain. EUROPEAN GUIDELINES FOR THE
      MANAGEMENT OF CHRONIC NON-SPECIFIC LOW BACK PAIN November 2004.

      Chou R, et al ; Clinical Efficacy Assessment Subcommittee of the American College of Physicians; American College of
      Physicians; American Pain Society Low Back Pain Guidelines Panel. Diagnosis and treatment of low back pain: a joint
      clinical practice guideline from the American College of Physicians and the American Pain Society. Ann Intern Med. 2007 Oct
       2;147(7):478-91.

      Sarno JE. Etiology of neck and back pain. J Nerv Ment Dis.1981;169:55-9.
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      Sherman KJ, et al. A Randomized Trial Comparing Yoga, Stretching, and a Self-care Book for Chronic Low Back Pain. Arch
       Intern Med. 2011 Dec 12;171(22):2019-26.

      Slipman CW, et al.Etiologies of failed back surgery syndrome. Pain Med. 2002;3:200-14
       Pearce JM. Aspects of the failed back syndrome: role of litigation. Spinal Cord. 2000;38:63-70.
       TodaYoshitaka. mpact of waist/hip ratio on the therapeutic efficacy of lumbosacral corsets for chronic muscular low back pain.
      Journal of Orthopaedic Science7:644-649,2002.

       浜西千秋.【腰痛に対する運動器リハビリテーション】 腰痛性疾患にみられる「コルセット筋」の筋力低下と簡便な座位
    トレーニング
.日本腰痛学会雑誌13 :52-57,2007.
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       temporospatial and fine structural correlates. Neuroscience. 1989;33(1):75-91.


46 回伊勢神経懇話会:2012516日(水)
症例報告:反復性過眠症(周期性傾眠症)の2症例 演者:宮崎眞佐男。座長:加藤保司。
 使用文献:
   The International Classification of Sleep Disorders Second Edition, American Academy of Sleep Medicine.2005.
   ②
九州神経精神医学48:103-108,2002.PLoS ONE. 2009;4(4):e5394. Epub 2009 Apr 30.(臨床神経学50:700-703,2010.
症例報告:外傷性脳損傷による認知症。演者:加藤保司。座長:小野直見
 使用文献:
   1)Dubois B, Slachevsky A, Litvan I, Pillon B. The FAB: a Frontal Assessment Battery at bedside. Neurology 2000;55:1621-1626.
   2)Grossman M, Koenig P, DeVita C, et al. The neural basis for category-specific knowledge: an fMRI study.
    euroimage 2002;15:936-948.

   3)藤井俊勝.Working memoryの神経機構.神経研究の進歩 2002;46:897-905.
   4)Halsband U, Ito N, Tanji J, et al. The role of premotor cortex and the supplementary motor area in the temporal control of
    movement in man. Brain 1993;116:243-266.

   5)Lepage M, Beaudoin G, Boulet C, et al: Frontal cortex and the programming of repetitive tapping movements in man: lesion
    effects and functional neuroimaging. Brain Res Cogn Brain Res. 1999;8:17-25.

症例報告:原発性局所(手掌)多汗症の1演者:宮崎眞佐男。座長:加藤保司。
 使用文献:
          H23年:難治性重症原発性局所多汗症の病態解析及び治療指針の確立研究班
          Haider A, Solish N. Focal hyperhidrosis: diagnosis and management. CMAJ. 2005 Jan 4;172:69-75
          原発性局所多汗症診療ガイドライン日本皮膚科学会誌120:1607-16252010
講演「臨床:Up to date」演者:宮崎眞佐男。座長:加藤保司。
【Ⅰ】脳過敏症候群. 使用文献
 ①清水俊彦. 片頭痛の最新治療戦略~新しい概念:脳過敏症候群を含めて~
  第
39回日本頭痛学会.ランチョンセミナー2011.
【Ⅱ】大気汚染と血管障害・認知症。 使用文献
    Wellenius GA,  et al. Ambient air pollution and the risk of acute ischemic stroke. Arch Intern Med. 2012 Feb 13;172:229-34.
    Weuve J, et al. Exposure to particulate air pollution and cognitive decline in older women. Arch Intern Med. 2012 Feb 13;172
     (3):219-27.

    Attfield MD, et al.The Diesel Exhaust in Miners Study: A Cohort Mortality Study With Emphasis on Lung Cancer.
     J Natl Cancer Inst. 2012 Mar 5.

【Ⅲ】むずむず腹」症候群.使用文献
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      Neurology.2011;77:1283-6.

     Allen RP, et al. Restless legs syndrome prevalence and impact: REST general population study. Arch Intern Med. 2005 Jun
      13;165(11):1286-92.

   ③  Hogl B, et al. KRestless legs syndrome: a community-based study of prevalence, severity, and risk
      factors. Neurology. 2005 Jun 14;64(11):1920-4.


45 回伊勢神経懇話会:2012425日(水)
症例報告:EDによる虚血性視神経症の一例。演者:宮崎眞佐男。座長:加藤保司。
 症例用まとめと文献
 J Neurol Neurosurg Psychiatry 2011:82:905-13、②臨床眼科 65:1319-1323.2011
 臨床眼科 58:1743-1747,2004、④Japanese Journal of Ophthalmoplogy48:158-162,2004
 抗アクアポクリン4抗体陽性視神経症
 ⑥山上明子らバイアグラ内服後に発症した虚血性視神経症の一例.神経眼科26:299-306,2009
   神経眼科25:327-342,2008
症例報告:両側中大脳動脈狭窄症の一例。演者:加藤保司。座長:小野直見
 使用文献:
 脳卒中治療ガイドライン2009
 Amarenco P.systematic review and up to date meta-analysis Stroke 2004;35:2902-2909
 Yadav JS. Protected Caroid-arterystending versus endeteractomy in high-risk patients. 
    NEJM 2004;351:1493-01
講演「パーキンソン病について」演者:宮崎眞佐男。座長:加藤保司。
 使用文献
 ①神経内科61171-1742004. Neurology.2007 Oct 23;69:1701-11 ③Lancet 2001
   Feb19;377;641-9
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   5:63-72, 1998.
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   49:242-5,2001.
Neurology. 2004;63:2170-2.Arch Neurol. 2004;61:837-838, 858-861.Neurology.
   2003;60:1761-6

44 回伊勢神経懇話会: 2012321日(水)
症例報告:アカシジア(Akathisia)を呈した1症例。演者:宮崎眞佐男。座長:加藤保司。
  Miller CHFleischhacker WWManaging Antipsychotic-Induced Acute and Chronic
  AkathisiaDrug Safety 2273-812000
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  ③上村誠:薬原性急性アカシジアの病態-薬原性錐体外路症状(EPS)と病態的に同根か-
 臨床精神病理 
539-452002
症例報告:音反響言語(Echolalia)を呈した1症例。演者:下村有利耶。座長:宮崎眞佐男。
 ①波多野和夫ら、精神医学
29967-9731987a
 ②Marcelo Bethierの分類(超皮質性失語:波多野和夫監訳,新興医学出版)
 ③MEDICAL REHABILITATION997-122008
 ④神経心理学22212-2182006. ⑤認知神経科学770-792005
 ⑥失語症研究20274-2792000
講演「認知症について」演者:宮崎眞佐男。座長:加藤保司。
 Christoffersen Met al. BMJ.2011 Sep 15343d5497
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  ②村山繁雄.FTD:前頭・側頭型認知症.神経病理学的研究の最前線.臨床神経,
  489982008
  ③久山町2002年(195例:科研:研究課題番号:14657047
  ④老年期痴呆研究会誌 1564-682010
 ⑤東京都ブレインバンク【545例:neuropathology2007 :27 578-584
 
⑥老年期認知症研究会誌 1761-652011. ⑦Vinters et alJNEN 592000
 Arch Neorol2004 61 1731-7. 
  2010年のFTLDの分類Mackenzie IRAet alActa Neuropathol 119 1-42010
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 神経内科 
70598-6002009
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43 回伊勢神経懇話会:2012215日(水)
症例報告:C2-4後縦靭帯骨化症の1例。演者:加藤保司。座長:小野直見
  1)月本裕国. 頚椎後縦靱帯化骨により脊髄圧迫症候を呈した1剖検例. 日外宝. 1960;29:1003-7.
  2Matsunaga S, Sakou T, Taketomi E, et al. Clinical course of patients with ossification of the posterior    
  longitudinal ligament: a minimum 10-year cohort study. J Neurosurg (Spine). 2004;100:245-8.

  3Matsunaga S, Nakamura K, Seichi A, et al. Radiographic predictors for the development of myelopathy in   
  patients with ossification of the posterior longitudinal ligament: a multicenter cohort study. Spine.   
  2008;33(24):2648-50.

  4Matsunaga S, Sakou T, Hayashi K, et al. Trauma-induced myelopathy in patients with ossification
  of the posterior longitudinal ligament. J Neurosurg. 2002;97:172-5.

症例呈示(Phobic postural vertigo・頸性めまい・ラクネ状態)と講演「めまい(私見)」
  演者:宮崎眞佐男。座長:加藤保司。
  1)Drachman DA, Hart CW. An approach to the dizzy patient. Neurology.
  1972 ;22(4):323-34
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  essential hypertensive patients. Hypertension 33:565-568,1999

  3)Brandt T. Phobic postural vertigo.Neurology.1996Jun;46:1515-9
  4)Equilibrium Res Vol68:218-225,2009

42 回伊勢神経懇話会:2012118日(水)
症例報告Hyperosteosis Frontalis Interna =Morgagni症候群。演者:宮崎眞佐男。座長:加藤保司。
 Am J Phys Anthropol109:303:-25,1999.脳神経49:899-904,1997
  Am J Phys Antropol 102:111-22,1997
症例報告:Isolated Neck M myositis1例。演者:加藤保司。座長:小野直見
 J Neurol Neurosurg Psychiatry 200374:683-686
症例報告:透明中核嚢胞+ベルガ腔の2。演者:宮崎眞佐男。座長:加藤保司。
 宮永和夫ら.精神医学27:43-49,1985講演「臨床:Up to date①筋トレとサルコペニア、②ヨーグルト」演者:宮崎眞佐男。座長:加藤保司。
  1)安田俊広・勝田茂. 中高年の筋力トレーニングは有効か. 総合臨床48102435-2436,1999
  2)Bidar S et al. Regular consumpution of vitamin D-fortified yogurt drink(Doogh)improve endothelial
 biomarkers in subjects with Type2 diabetes: Arandomazed Double-blind clnical trial.BMC Med.2011 Nov     
  24;9(1):125.doi:10.1186/1741-7015-9-125

  3)葛谷 雅文.サルコペニアの疫学、診断.日労医誌2011;48:44-46.

41 回伊勢神経懇話会:20111130日(水)
症例報告:左中心後回新鮮ラクネ梗塞:MRIによる発症日推測。演者:加藤保司。座長:小野直見  
  Petkova M, Rodrigo S, Lamy C, Oppenheim G, et al.MR imaging helps predict time from symptom onset
  in patients  with acute stroke : implications for patients with unknown onset time. Radiology.2010
  Dec;257(3):782-92.

症例報告:
透明中隔嚢胞+脳梁部分欠損からのHY的右手脱力。演者:宮崎眞佐男。座長:加藤保司。 Tanaka Y, Albert ML, Miyazaki M, Fujita K.Pseudohysterical hemiparesis.  J Nerv Ment Dis.2007    
  Oct;195(10):874-6

症例報告:左手デュピュイトラン(Dupuytren)拘縮の1例。演者:畠中節夫。座長:宮崎眞佐男
 1)今澤良精ら.整形外科と災害外科50:167-169,2001.
 2)平澤泰介ら.整形・災害外科28:429-437,1985.
 ) 大野克記ら.日本手外科学会雑誌27:665-669,2011.
 )  NotbohmHolger et al.The Journal of Biochemistry 118:405-410,1995.
 5)KozmaEwa Maria et al. The Journal of Biochemistry 137:463-476,2005.
 6)中島紀綱ら、日本手外科学会雑誌27:269-271,2010.
 7)大井宏之ら、日本手外科学会雑誌26:510-512,2010.
 8)de Quervain DJ. Proc Natl Acad Sci USA,.2011 Apr19 108(16):6621-5
講演「臨床:Up to dateVEの功罪、②メタボの功罪、」演者:宮崎眞佐男。座長:加藤保司。
  1)Miller ER 3rd, Pastor-Barriuso R, Dalai D, Riemersma RA,et al.   Meta-analysis : high-dosage vitamin E   
  supplementation may increase all-cause mortality. Ann Intern Med. 2005 Jan 4;142(1):37-46.

  2)Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment.Petersen RC, et al &;Alzheimer’s
  Disease Cooperative Study Group. N Engl J Med 2005;352:2379-88

  3)Vitamin E and the risk of prostate cancer:the Selenium and Vitamin E Cancer Prevebtion Trial (SELECT).
  Klein EA,Thompson IM Jr,tangen CM,Crowley JJ,et al. JAMA.2011 Oct 12;306(14):1549-56.

  4)Supraphysiological hyperinsulimaemie is necessary to stimulate skeletal muscle protein anabolism in older
  adults : evidence of a true age-related insulin resistance of muscle protein metabolism.  Fujita S, Glynn EL,   
  Timmerman KL, Rasmussen BB, Volpi E.  Diabetologia.2009 Sep:52(9):1889-98.

  5)Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity:A Possible Contributor to Increased
  Risk of Cardiovascular Disease in Diabetes.  Rabbani N, Godfrey L, Xue M, Shaheen F, et al.  Diabetes.2011
  May 26.

40 回伊勢神経懇話会:20111019日(水)
症例報告:アミロイド血管症からの繰り返す脳出血。演者:宮崎眞佐男。座長:加藤保司。
  ①浜口 毅、山田正仁 脳と神経601275-12832008
 ②Pezzini A, Del Zotto E, Volonghi I, Giossi A, Costa P, Padovani A. Cerebral amyloid angiopathy: a common
  cause  of cerebral hemorrhage. Curr Med Chem. 2009;16(20):2498-513

  Chung YA, et al. Hypoperfusion and Ischemia in Cerebral Amyloid Angiopathy Documented by
  99mTc-ECD Brain Perfusion SPECT. J Nucl Med. Dec 2009;50(12):1969-74.

  Oh U, Gupta R, Krakauer JW, et al. Reversible leukoencephalopathy assosiated with cerebral amyloid   
  angiopathy.
Neurology.Feb 10 2004;62(3)494-7
  Cano LM et alReversible acute leukoencephalopathy as a form of presentation in cerebral amyloid
  angiopathy
J Neurol SciOct 22 2009;
   Greenberg SMCerebral amyloid angiopathyprospects for clinical diagnosis and treatment
  NeurologySep 1998;51(3):690-4.
   Yamashita Tet alEffect of liver transplantation on transthyretin Tyr114Cys-related cerebral amyloid     
  angiopathy
NeurologyJan 8 2008;70(2):123-8
   ⑧吉田光宏,山田正仁,脳血管疾患の診断の最前線 脳アミロイドアンギオパチー 
 病態と診断法の進歩.医学のあゆみ
231445-4512009
症例報告:むずむず足症候群(Restless leg syndrome。演者:加藤保司。座長:小野直見
    Bogan RK, et al; TREAT RLS US Study Group.Ropinirole in the treatment of patients with restless legs
  syndrome: a US-based randomized, double-blind, placebo-controlled clinical trial.Mayo Clin Proc. 2006   
  Jan;81(1):17-27.

症例報告:Mega cauda equine症候群。演者:加藤保司。座長:小野直見
  ①小山素麻呂:末梢神経・脊髄の外科、P209-211
  PIA HW. Megacauda; a congenital enlargement of the caudal sac in the lumbosacral area.
  Langenbecks Arch Klin Chir Ver Dtsch Z Chir. 1959;290:429-39.

講演「DiazepamUp to date」演者:宮崎眞佐男。座長:加藤保司。
  1)Allegulander Cet alWorld Council of AnxietyWCA recommendations for the long-term treatment
  of generalized anxiety disorder
ACNS Spectr2003 Aug8(8 Suppl 1):53-61.
  2)Inomata Set alCYP2C19 genotype affects diazepam pharmacokinetics and emergence from general
 anesthesia
Clin Pharmacol Ther200578647-55.
  3)Tassaneeyakul Wet alAnalysis of the CYP2C19 polymorphism in a North-eastern Thai
  population
Pharmacogenetics200212221-5
  4)Grower MFRussell EA JrGetter LSolubility of injectable Valium in intravenous solutions
  Anesth Prog
1978 Sep-Oct255】:158-60

39 回伊勢神経懇話会:2011年7月27日(水)
講演「認知症概略・問診の嘘・スケール使用について」演者:宮崎眞佐男。座長:田中民弥。
  1)日本神経学会痴呆治療ガイドライン
  2)改訂長谷川式簡易知能評価スケール(HDS-R)の作成.老年精神医学雑誌 2:1339-1347.1991 
  3)老人用簡易知能検査法としてのKohsテストの有用性と問題点. 精神医学における臨床心理学 
 金剛出版pp
151-164,1978
  4)esteban-santillan,c.Praditsuwan,R,Ueda,HGeldmacher,D.SClock drawing test in very mild Alzheimer's
  disease. Jounal of the American Geriatrics society,46:1226-1269,1998

  5)痴呆症臨床における時計描画検査の有用性.バイオメディカル ファジィ システム学会誌    
  6:69-79,2004

  6)WAIS-Rを用いた軽度認知症鑑別の試み.老年精神医学雑誌 11:289-297,2000
  7)認知症スクリーニング検査.広島修大論集第48巻347-379,2007
  8) 問診(患者の嘘)医療者患者間コミュニケーション事情調査H22,3,31. 株式会社 Q-life
講演「DM食事療法・Glycemic Indexに関して」演者:加藤保司。座長:小野直見
 Human Nutrition Unit, Schooln of Molecular and Microbial Biosciences,University of Syndey
講演「熱中症・重症度診断」演者:宮崎眞佐男。座長:加藤保司。
 1)日救急医学会誌2008:19:309-21. 2)Int J spots Med 19:146,1998. 3)臨脳38:730,1996.
  4)日臨内誌11:188,96.5)Clin Exp Pharmacol Physiol 26:286.99.6)Cirt Rev Immunol 19:285,99

38 回伊勢神経懇話会:2011615()
症例報告:Failed back (Surgery) Syndrome (FBSS)。演者:宮崎眞佐男。座長:加藤保司。
  1)Hubert L.Rosomoff.17回米国疼痛学会.2001. 2)James N.Campbell:17回米国疼痛学会.2001. 3)
 ペインクリニック
30:S591-S600,2009.別冊. 4)Pearce JM.Aspects of the failed back syndrome:role of    
  litigation.Spinal Cord.2000;38:63-70. 5)JAMA.2006.22;296:2441-50.

  6)Slipman CW,et al.Etiologies of failed back surgery syndrome.Pain Med.2002;3:200-14.
  7)Neurosurgery.2005;56(1):98-106

症例報告:神経調節性失神型めまいとめまい・リハビリ。演者:加藤保司。座長:小野直見
  1)五島史行ら、末梢性めまい疾患におけるVertigo handicap questionnaire(VHQ)の日本語版の信頼性、
 妥当性の検討
.Equilibrium Research69:412-417,2010.
  2)新井基洋.めまいの理学療法 めまいリハビリテーションの紹介.医学の歩み235:917-920,2010.
  3)Romero-Ortuno R,Cogan L,Foran T,Kenny RA,Fan CW. Continuous noninvasive orthostatic blood
  pressure measurements and their relationship with orthostatic intolerance,falls,and frailty in older people.
  J Am Geriatr Soc.2011 Apr;59(4):655-65.

講演「変形視概略」演者:宮崎眞佐男。座長:田中民弥。
  1)藤兼正明 .90°回転した変形視を呈した橋傍正中部梗塞の1症例. 神経内科Vol.50 No.6    
  Page.576-579 1999

  2)上久保毅ら,長期に及ぶ井変形視をきたした多発性脳梗塞の1例神経研究の進歩60:671-675,2008
  3)齋藤博ら,左半側視野に空間視異常(変形視)を反復したてんかんの1.臨床神経心理16:43-48,2005.12   4)長谷部誠ら,右視野に反復性幻覚を認めた1. 臨床神経心理12:37-42,2001.
  5)中里良彦ら,前兆を伴う拍動性頭痛、視覚保続、変形視を呈した側頭葉梗塞による症候性
 てんかんの
1 例.神経内科67:268-272,2007.
  6)勝又康弘ら,不思議の国のアリス症候群を呈した1.臨床神経心理11:53-55,2000.

37 回伊勢神経懇話会2011525
症例報告:慢性頭痛の4例。演者:宮崎眞佐男。座長:小野直見。
  1)国際頭痛分類第22004(ICHD-) 診断基準.Headache198525194-198.& 
 Neurol Sci 200425(Suppl3)255-257
  2)慢性疼痛2931-373)2010.日本頭痛学会2005年ガイドライン.4)日医雑誌 2001126
 393-396 5)Headache 199131321-. 6)Headache200040142-136.
  7)Am J Public Health 2002Oct92(10)1657-61   
  8)Stead WWHeymqn AThompson HKHammond WEComputer Assisted Intewiew of Patients With    
  Functionnal Headache
Arch Intern Med 1972;129950-955
  9)Quinn CChandler CMoraska AMassage therapy and frequency of chronic tension headaches. 
 Am J Public Health2002Oct92(10)1657-61
症例報告:認知症の予後について。演者:加藤保司。座長:小野直見
  Rait GWalters KBottomley CPetersen Iet al. Survival of people with clinical diagnosis of
  dementia in primary care
cohort studyBMJ2010 Aug5341c3584doi10
症例報告:音楽性幻聴。演者:下村有利耶。座長:宮崎眞佐男。
   姉川孝.側頭葉性幻聴.神経内科53:528-534,2000
   姉川孝, 原健二, 山本兼司, .左側頭葉虚血により一過性に一側性幻聴をきたした1.
  臨床神経学
3510 Page1137-1141(1995.10)
講演「椎体圧迫骨折概略」演者:宮崎眞佐男。座長:田中民弥
 1) J Bone Miner Res181547-532003. 2)日骨代謝誌1876-822001. 3)J bone miner metab22
 
104-102004.4) Lancet 3481535-411996.  5)関東整形災害外科学会雑誌23450-4551992.
  6)整形・災害外科411529-15361998.

36 回伊勢神経懇話会:2011119日(水)
症例報告:L5潜在性二分脊椎。演者:宮崎眞佐男。座長:小野直見。
  1) 脳と発達41:191-196,2009
  2) International Journal of Urology14:33-38, 2007
症例報告:左>右内頸動脈Fibro-Muscular Dysplasia(FMD)。演者:加藤保司。座長:小野直見
  1) Acta Chir Belg 99:163,1999
  2) Resta M,Gentile MA,Cuonzo FD:Clinical-angiographic correlations in 132 patients with   
  megadolichovertebrobasilar anomaly. Neuroradiology 26:213-216,1984

症例報告:陳旧性ウィルス性脊髄炎の一例。演者:宮崎眞佐男 座長:加藤保司。
  1) Clin Neurophysiol 113:1778,2002,Clin Neurophysiol 113:656,2002
  2) Br J Anaesth88:362,2002. 3) Neuroimage17:1347,2002

35 回伊勢神経懇話会2011316
症例報告:尾状核を主体とした血管障害による大脳障害。演者:宮崎眞佐男。座長:小野直見。
 1) Science.2006;312:1537-40. 2)Mov Disord.2006.21:1326-3132.
  3)Arch Gen Psychiatry 2005;62:371-8. 4)神内 53:535-540,2001. 5)精神医学27:1185-1193,1985
  6)日本老年医学会雑誌 45:615-621,2008. 7)臨床神経学37:1014-1020,1997.
  8) 神経内科58:86-88,2003
症例報告:droopy shoulder(肩下がり)症候群。演者:加藤保司。座長:小野直見
 1)Clein LJ.The dropy shoulder syndrome. Can Med AssocJ.1976 Feb 21;114(4)343-4.
  2)Thomas R.et al.  The droopy shoulder syndrome.     Neurology1984;34:212.
  3)山鹿真紀夫 :肩こり・胸郭出口症候群、整形外科 Vol56 No8 P929-9352005
  4)山鹿真紀夫、高木克公、片岡泰文:胸郭出口症候群,整形外科非観血的治療法の骨のコツ(上).
 第1版P18-21 全日本病院出版会.1996
  5)片岡泰文ら. The Droopy Shoulder Syndromeの検討.肩関節、Vol 14 No1 P56-59 1990
  6)土山、他:Droopy shoulder syndrome. 神経内科 38:420-421 1993
症例報告:頭部外傷後耳鳴りの一例。演者:宮崎眞佐男 座長:加藤保司。
 Houdart,E.Aneurysm of a Dural Sigmoid Sinus:A Novel Vascular Cause of Pulsatile TinnitusAnn Neurol   
  48:669-671,2000

34 回伊勢神経懇話会:2011216()
症例報告:脳梗塞慢性期のヒスタミン治療。演者:宮崎眞佐男 座長:田中民弥
  1)セロトニン-モノアミン-オキシダーゼとヒスタミン-ジアミン-オキシダーゼ系
   (Zn Nervopathol Psikiatr Im 80:1164-1170,1980
  2)実験系(J Neural Transm 50:225-232,1981.)否定的実験(J Neurotrauma 10:83-89,1993.
症例報告:不随意運動の4例。演者:加藤保司。座長:宮崎眞佐男
  1)パーキンソン病(神経治療学15:301-308,1998.2)本態性振戦(神内54:551-556,2001.
  3)周期性四肢運動障害 (神内48:271-273,1998.
症例報告:脳梗塞急性期患者における生体リズムと慢性期の機能予後。
  演者:宮崎眞佐男。座長:小野直見。
  1) 自律神経40:30-35,2003.Psychiatry2)Clin Neurosci.2002;56:221-2.

33 回伊勢神経懇話会2011119
症例報告:アルツハイマー型認知症の初期例。演者:宮崎眞佐男 座長:田中民弥
  1)Matsunari I,Samuraki M,Chen W-P,Yanase D,et.al.Comparison of 18F-FDG PET and optimized  
  voxel-basedMorphometry for detection of Alzheimer’s disease:Aging effect onDiagnostic performance.
  J Nucl Med 2007 Dec;48(12):1961-70

  2)Raina P,Santaguida P,Ismaila A,Patterson C,et al..Effectiveness of cholinesterase inhibitors and
  memantine  
  forTreating dementia:evidence review for a clinical practice guideline. Ann Intern Med.2008 Mar 4;148(5):
  379-97

症例報告:前頭側頭型認知症。演者:加藤保司。座長:宮崎眞佐男

  1)Cherkas LF,Hunkin JL,Kato BS,Richards JB,et.al.The association between physical activity in leisure time
  and leukocyte Telomere length. Arch Intern Med. 28;168(2):154-8.2008

  2)村上繁雄.FTD:前頭・側頭型認知症.神経病理学的研究の最前線.489982008
  3)Neary D,et.al.Frontotemporal lobar degeneration:a consensus on clinical diagnostic criteria.Neurology.1998
  Dec;51(6):1546-54

  4)Kramer JH,et.al.Distinctive neuropsychological patterns in frontotemporal dementia,semantic dementia,
  and Alzheimer disease.Cogn Behav Neurol.2003;16:211-8.

症例報告:Lewy小体病。演者:下村有利耶。座長:宮崎眞佐男。
  1)Nagahama Y,Okina T,Suzuki N,Matsuda M,Fukao K,Murai T.Classification of psychotic symptoms in
  dementia with lewy bodies. Am J Geriatr Psychiatry.2007 Nov;15(11):961-7

  2)Da Silva JA,et.al.Safety of low dose glucocorticoid treatment in rheumatoid arthritis:published evidence
  and prospective trial data. Ann Rheum Dis.2006 Mar;65(3):285-93.

  3)Rothwell PM,Fowkes FG,Belch JF,Ogawa H,et.al.Effect of daily aspirin on long-term risk of death due to   
  cancer:analysis of individual patient data from randomized trials. Lancet.2011 Jan 1;377(9759):31-41.

32回伊勢神経懇話会:20101117日(水)
症例報告:アミロイドアンギオパチーの一例。演者:加藤保司。座長:宮崎眞佐男
 Ann Neurol 2007 Sep;62(3):229-34.
症例報告:ラクネ状態:診断の変遷。演者:宮崎眞佐男 座長:田中民弥
  1)N Engl J Med. 2010 May 20;362(20):1863-71.1930-1.
  2)e-medicine from WebMD professional Updated:Feb 24,2010.
  3)亀山正邦Clinician 1990:No390.358-362
症例報告:Capgras症候群を呈した1例。演者:下村有利耶。座長:宮崎眞佐男
  1)Diesfeldt, H. F. A. and Troost, D. Dementia 62(2),94-98.1995
  2)Nagahama Y, et al.Brain.2010 Feb;133:557-67

31回伊勢神経懇話会:20101020日(水)
症例報告:Fahr病の一例。演者:宮崎眞佐男 座長:田中民弥 
 Oliveira JR,SpiteriE,SobridoMJ,HopferS,et alGenetic heterogeneity in familial idiopathic basal.ganglia    
  calcification(Fahr disease.Neurology.2004Dec14;63(11):2165-7

症例報告:パーキンソン病・症候群のMIBG myocardial scintigraphy
  演者:加藤保司。座長:宮崎眞佐男
  1)Nagayama H,Hamamoto M,UedaM,NagashimaJ,KatayamaY.Reliability of MIBG myocardial scintigraphy
   in the diagnosis of Parkinson's disease. J Neurol Neurosurg Psychiatry.2005;76:249-51

   2) IshibashiK,SaitoY,MurayamaS,KnemaruK, et al.Validation of cardiac 123I-MIBG scintigraphy in patients
  with  Parkinson's disease who were diagnosed with dopamine PET.Eur J Nucl Med Mol Imaging 2010 Jan     
  ;37(1):3.11

症例報告:EBウイルス性多発神経炎・左下肢Iivedo reticularisの一例。
 演者:宮崎眞佐男 座長:加藤保司。
  1)Corssmit EP, Leverstein-van Hall MA,Portegies P,BankkerP.Severe  neurological complication in
  association withEpstein-Barr virus infection.J  Neurovirol.1997Dec;3(6)460
4.
  2)Gavin C,LanganY,HutchinsonM.Clinical and peripheral neuropathy due to Epstein-Barr virus infection.
   Postgrad MedJ.1997Jul;73(861):419-20

30回伊勢神経懇話会:2010年7月21日(水)
症例報告:左前頭葉下面髄膜腫の1例。演者:宮崎眞佐男。座長:小野直見。
 Yano S, Kuratsu J; Kumamoto Brain Tumor Research Group. Indications for surgery in patients
  with asymptomatic meningiomas based on an extensive experience.
J Neurosurg. 2006 Oct;105(4):538-43.
症例報告:パーキンソン病の病的賭博。演者:加藤保司。座長:宮崎眞佐男
  1)Dodd ML,Klos KJ,Bower JH,Geda YE,josephs KA,Ahlskog JE.Pathological gambling caused by drugs
  used to treat Parkinson disease.Arch Neurol.2005 Sep;62(9):1377-81.

  2)Voon V,Thomsen T,Miyasaki JM,de Souza M,Shafro A,Fox SH,et al.Factors associated with
  dopaminergic drug-related pathological gambling in Parkinson disease.Arch Neurol.2007 Feb;64(2):212-6..

症例報告:パーキンソン病に伴う首下がり病。演者:宮崎眞佐男 座長:加藤保司。
  1)Fujimoto K.Dropped head in Parkinson’s disease.J Neurol.2006 Dec;253 Suppl 7:Vii21-vii26.
  2)斉藤豊和.頚部筋障害による首下がり.神経内科, 51 : 13-19,1999
講演「臨床up to date」演者:宮崎眞佐男。座長:田中民弥
  1)The ACCORD Study Group.Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus.
  N Engl J Med 2010;362:1563-74.

  2)O’Donnell MJ, et al; INTERSTROKE investigators.Risk factors for ischaemic and intracerebral
  haemorrhagic stroke in 22 countries(the INTERSTROKE Study):a case-control study. Lancet.2010
  Jul 10;376(9735):112-23.

  3)Wilkens P,Scheel IB,Grundnes O,Hellum C,Storheim K. Effect of glucosamine on pain-related disability
   in patients with chronic low back pain and degenerative lumbar osteoarthritis :a randomized controlled
  trial. JAMA.2010 Jul 7;304(1):45-52.

  4)Elliott P,Toledano MB, Bennett J,Beale L,et al.Mobile phone base stations and early childhood    
  cancers:case-control study. BMJ.2010 Jun22;340:c3077.doi:10.1136/bmj.c3077.

  5)Wu FC,et al;the EMAS Group.Identification of Late-Onset Hypogonadism in Middle-Aged and Elderly Men.
  N Engl J Med.2010 Jun 16..

  6)Ehara N,Morimoto T,Furukawa Y,Shizuta S,et al.Effect of baseline glycemic level on long-term
  cardiovascular outcomes after coronary revascularization therapy in patients with type 2 diabetes mellitus
  treated with hypoglycemic agents.Am J Cardiol.2010 Apr 1 :105(7) :960-6.

29回伊勢神経懇話会:2010818日(水)
症例報告:Occipitalzation of Atlasの一例。演者:宮崎眞佐男 座長:加藤保司。
症例報告:新鮮梗塞の外来治療。演者:加藤保司。座長:宮崎眞佐男
 1)Lampl Y,Boaz M,Gilad R,Lorberboym M,et.al. Minocycline treatment in acute stroke:an   
  open-label,evaluator-blinded study. Neurology. 69(14):1404-10.2008

   2) Hashioka S,Klegeris A,McGeer PL,et al. Proton Pomp inhibitors exert anti-inflammatory
  effect and decrease human Microglial and monocytic THP-1 cell neurotoxicity. Exp
  Neurol.217(1):177-83.2009
   3)There’s no place like home:an evaluation of early supported discharge for stroke.
    Stroke.31(10):2521-2.2000
講演「軽度熱中症について」演者:宮崎眞佐男。座長:小野直見
  Clinical neurology  chap28:p53、② Am Fam Physici 58:749,1998
   Int J sports Med 19:146,1998、④臨脳 38:730,1996.⑤日臨内誌 11:188,1996
   Clin Exp Pharmacol Physiol 26 :826,1999.⑦ Cirt Rev Immunol 19 :285,1999
   Int J sports Med 19 :150,1998.⑨ Aviat Space Env Med 70 :987,1999

28回伊勢神経懇話会:2010年7月21日(水)
症例報告:Parasomnia (睡眠時随伴症)の4例. 演者:宮崎眞佐男 座長:加藤保司。
  1)Kaplan:ComprehensiveTextbookPsychiatry.7ed[27,p.1692],)現代臨床精神医学8[67,p.304]
症例報告:夜間摂食症候群 nocturnal eating syndromeの1例.演者:加藤保司。座長:畠中 節夫
  1) Nirenberg MJ, Waters C. Nocturnal eating in restless legs syndrome.Mov Disord. 2010 Jan 15;25(1):126-7.
  2)Vetrugno R, et al. Nocturnal eating:sleep-related eating disorder or night eating syndromeA    
   videopolysomnographic study. Sleep.2006 Jul 1;29(7):949-54.

症例報告:Non-REM睡眠関連異常運動・睡眠時歯ぎしり:Sleep Bruxismの1例
   演者:宮崎眞佐男。座長:田中 民弥

27回伊勢神経懇話会:22010623日(水)
講演「ラクネ状態の臨床」演者:宮崎眞佐男 座長:加藤保司。
  1)臨床症侯からみた軽脳梗塞-TIA・ラクネをめぐって-亀山 正邦 clinician 1990:No390.358-362  
  2)Multiple lacunar state
の臨床的検討.田代邦雄、沢村豊、松本照久、脳と神経36475-480,1984 
  3)lacunar stateによる脳血管性痴呆の臨床病理学的検討・20剖検例の病巣分布と症状の対比
  石井惟友、西原康雄、今村司、精神医学27:1185-1193,1985
症例報告:シュモール結節の3例。 演者:加藤保司。座長:宮崎眞佐男
 シュモール結節(Schmorl node)(機序)岡本 純  OsteoporosisJapan15:173-180,2007
 (病理学的変化)yasuma T,Saito S,kihara K,Acta  Pathologica Japonica 38:723-733,1988
 (腰痛との関係)原田博文、泊一秀、若年者の腰痛MRI像の検討。整形外科と災害外科
  39
436-440,1990
症例報告:老人性筋萎縮(sarcopenia)の1例。演者:宮崎眞佐男。座長:小野直見
 1)Histochemical study on the changes in muscle fibers in relation to the effects of aging on recovery
  from muscular atrophy caused by disuse in rats tanaka toshiya,Kariya yusei ,Hoshino yuichi. ournal
  of Orthopaedics Science 9:76-85,2004

  2)Discontinious capillary segments in the extensor digitorum longus muscle of aged BUF/Mna ratsDesaki   
  Junzo,EzakiTaichi.journal of Electron Microscopy 51:425-439,2002

26回伊勢神経懇話会:2010526()
症例報告:ウィルス性筋炎。演者:加藤保司。座長:宮崎眞佐男
講演:「所謂風邪と末梢神経障害・筋障害」演者:宮崎眞佐男 座長:加藤保司。 
  使用文献:①顔面神経麻痺(
Laryngoscope 88 :787-801,1978.)②前庭神経障害(Ann N Y Acid Sci    
   956:306-13,2002.
)③Benign cranial polyneuropathy(Laryngoscope 88 :787-801,1978.)④視神経炎
 (
Rev NeurolParis137393-413,1981.)⑤Bilateral brachial plexus neuritis (Ann Neurol 40:928
   -32,1996.
 J Emerg Med18:177-9,2000.) suprascapular neuropathy(Clin Orthop 386 :131-8,2001.) 
  ⑦
mononeurritis multiplex(.臨神39 :465-467,1999. 臨神36 :358-361,1996..) mono-and polyradiculo
   neuritis
Epstein-Barr virus(J Neurol Sci28 :115-20,1976.) ⑧Non-A,non-B(Dtsch Med Wochenschr   
   109:1160-4,1984.)
rubellaRev Nurol(Paris)140:665-8,1984.GBS like (JMedVirol21:207-16,1987.
   Rev Neurol (Paris)137:393-413,1981.
脳神経42:245-251,1990)
症例報告:マイオジールによる脳幹部化学的炎症由来の不整脈・精神運動発作
 演者:加藤保司。座長:宮崎眞佐男
  Granulomatous meningitis as a late complication of iodized oil myelography.Ruberu NN,Saito Y Honma
  N,Sawabe M,Yamanouti H,Murayama S. Neuropathology.2004 Jun;24(2):144-8.

症例報告:オリーブ・橋・小脳変性症とThe Hot Cross Bun Sign。演者宮崎眞佐男。座長:小野直見
 The Hot Cross Bun Sign. Radiology:Volume245:Number 2-November 2007

25回伊勢神経懇話会2010421
症例報告左内包後脚ラクネ梗塞(ataxic hemiparesis) 1
  演者宮崎眞佐男 座長加藤保司。使用文献
  Chalela JA,Kidwell CS,Nentwich LM,Luby M,et.al.Magnetic resonance imaging and computed
   tomography in emergency Assessment of patients with suspected acute stroke:a prospective 
  
comparison.
Lancet 27;369(9558):293-8.2007
   Lampl Y,Boaz M,Gilad R,Lorberboym,et al. Minocycline treatment in acute stroke :an open-label,    
  Evaluator-blinded study. Neurology.69(14):1404-10.2007

  Hashioka S,Klegeris A,McGeer PL. Proton pump inhibitors exert anti-inflammatory effects and
   decrease Human microglial and monocytic THP-1 cell neurotoxicity.
Exp Neurol 217(1):177-83.2009
症例報告:ストレスによる起立性調節障害検査.演者:宮崎眞佐男 座長:加藤保司。
  Cherkas LF,Hunkin JL,Kato BS,Richards JB,et.al.The association between physical activity in
   leisure time and leukocyte Telomere length. Arch Intern Med. 28;168(2):154-8.2008

   Arch Intern Med 163:361-366.2005 J Am Geriatr Soc 54:912-918.2006 J Am Geriatr Soc
   55:383-388.2007  N Eng J Med 358:1887-1898.2008

症例報告前頭-側頭型認知症depressive form演者:加藤保司。座長:宮崎眞佐男         
  Ehlenbach WJ,Hough CL,Crane PK,Haneuse SJ,et al. Association between acute care and critical
   illness hospitalization  And cognitive function in older adults. JAMA 303(8):763-70.2010

  Mayo NE,Wood-Dauphinee S,Cote R,Gayton D,Carlton J,Buttery J,Tamblyn R. There’s no place like
   home:an evaluation of early supported discharge for stroke. Stroke 31(10):2521-2.2000

24回伊勢神経懇話会:2010317日(水)
症例報告:アルツハイマー初期の1例.演者:加藤保司。座長:宮崎眞佐男
  川田憲一、宮﨑眞佐男、葛原茂樹, 右視床梗塞により一過性の人形現象を呈した1例.
 臨床神経学
42:922-924,2002
症例報告:運動時発作(Kinesiogenic Attack) 1例.演者:宮崎眞佐男 座長:加藤保司。
  Neurology. 2004 Dec28; 63(12):2280-7.
症例報告:認知症患者の異痛症(Allodynia)演者:宮崎眞佐男。座長:小野直見
  Miraucourt LS,et al.J Neurosci.2009 Feb 25;29(8):2519-27.

23 回伊勢神経懇話会:2010217日(水)
症例報告:嗅覚障害(unknown cause)の1例.演者:宮崎眞佐男。座長:小野直見
  Treatment of postviral olfactory loss with glucocorticoids,ginkgobiloba,and mometasone nasal spray.
  Seo BS Lee HJ, Mo JH, Lee CH, et al. Arch Otolaryngol Head Neck Surg. 2009 Oct;135(10):1000-4
 
症例報告:2型DMretinopathyNephropathyAmyotrophy+ central pontine mylinoysis1例.
 演者:加藤保司。座長:宮崎眞佐男。使用文献

  bernard messert et al.Central pontine myelinolysis Consideration on etiology,diagnosis,and                treatment.NEUROLOGY 1979;29:147.②臨床神経47:173-176,2007
 ③日本内科学会誌 
96:2291-2293,2007

22回伊勢神経懇話会:2010120()
症例報告:うつ状態による軽度認知障害の1例.演者:加藤保司。座長:宮崎眞佐男
  Cerebral sinovenous thrombosis in children. De Veeber G,Andrew M,Adams C,Bjornson B,Booth F,
  Buckley DJ,et al.N Engl J Med. 2001 Aug 9;345(6):417-23.

症例報告:心房細動からの認知障害?の1例.演者:宮崎眞佐男 座長:加藤保司。
  ) Vascular demntia may be the most common form of dementia in the elderly.Roman GC.
   J Neurol Sci.2002 Nov 15;203-204:7-10

   2 Heart disease and vasucular risk factors in the cognitively impaired elderly:implications for
   Alzheimer
s dementia . Polidori MC,Marvardi M,Cherubini A,Senin U ,Mecocci P.
   Aging (Milano). 2001 Jun;13(3):231-9.

症例報告
Crowned dens syndrome1例.演者:宮崎眞佐男。座長:小野直見
  ①飛田哲郎ら.Crowned dens syndrome 後頭部の激痛で発症する偽痛風発作.
  日本脊髄障害医学会雑誌 
21:116-1172008
  ②久保田元ら、頭蓋頚椎移行部におけるCrowned dens像.臨床放射線13:1777-17822007
  ③小林孝ら.環軸関節穿刺・注射で軽快する急性頸部痛 Crowned dens  syndrome
  臨床整形外科
43:369-3732008
  ④大村真弘ら.後頭後頸部痛のみを呈し3次元CT血管像が診断に有用であった特発性
  椎骨動脈解離性動脈瘤の
1例.臨床神経学46:160-1622006
  ⑤今井昇ら.側頭動脈炎における頭痛・頸部痛・顔面痛についての検討.
  日本頭痛学会誌
30:129-1302003

21回伊勢神経懇話会:20091118日(水)
症例報告:Vertigenous Epi(めまいてんかん)1例.演者:宮崎眞佐男 座長:加藤保司。
  Bladin,P.F. Epilepsia 39(4):442-7.1998 ②Blanke,O.,S.Perrig,et.al.JNNP 69(4):553-6.2000
  Kahane,P.,D.Hoffmann,et.al. Ann Neurol 54(5):615-24.2003Laff R,Mesad S snd Devinsky O.
    Nuerology 61(9):1262-4.2003 ⑤Wiest,G.,F.Zimprich,et.al. Neurology 62(3):473-5.2004
症例報告:drop stack or TGA1例.
症例報告:失立発作or drop attack1例.
  演者:加藤保司。座長:宮崎眞佐男。使用文献
  Ishiyama G, and others. Neurology 57:1103-1105.2001
   Sheldon JH. BMJ 2:1685-90.1960 “On the natural history of falls in old age.”
   Tumarkin,A. BMJ 1:175-77.1936 “The otolithic catastrophe:a new syndrome.”

20回伊勢神経懇話会:20091021日(水)
症例報告:眩暈と間違われる症例(眩暈を主訴として変形視を呈した3症例)
 演者:宮崎眞佐男 座長:加藤保司。
  )上久保毅ら,長期に及ぶ変形視をきたした多発性脳梗塞の1例 
  神経研究の進歩
60:671-675,2008
  )齋藤博ら,左半側視野に空間視異常(変形視)を反復したてんかんの1例.臨床神経心理
  16:43-48,2005.12)

症例報告Megacysterna magna2症例演者:加藤保司。座長:宮崎眞佐男
   1)CT研究6:21-26,1984.
   2)日本先天代謝異常学会雑誌18:31-40,2002.
   3)日本新生児学会雑誌23:464-472,1987.

19回伊勢神経懇話会:2009916日(水)
症例報告 painfull legs&moving toe syndrome 1例.演者:宮崎眞佐男 座長:加藤保司。
  Pla ME,Dillingham TR,spellman NT,Colon E,Jabbari B. painfull  legs and moving toes associates
  with tarsal tunnel syndrome and accesary soleus muscle.  mov disord.1996 Jan:11(1) 82-6

   佐橋 巧 他 painful legs and moving toes.の足指不随意運動発現機序 臨床神経学
  9:849-853,1989.
  Aizawa H. Gabapentin forpainful legs and moving toe syndrome. Internal Medicine 46:1937,2007
  ④峠 哲男 他. Painful legs and moving toesと両下肢にひろがる有痛性筋収縮を呈した
  アルコール性多発ニューロパチーの1例 臨床神経学 
38:762-766,1998
症例報告:新鮮右前頭葉ラクネ梗塞にミノマイシン治療.演者:加藤保司。座長:宮崎眞佐男
 There`s no place like home:an evaluation of early supported discharge for stroke stroke.
  2000 Oct ;31(10):2521-2

  A Randomized Trial of Low-Dose Aspirin in  the primary Prevention of Cardiovascular disease in
  Women  Paul M Ridker, NEJM March 7,2005

  Minocycline treatment in acute stroke:an open-label,evaluator-blinded study Lampl Y,Boaz M,Gilad
   R,Lorberboym M,et al.  Neurology.2007 Oct 2;69(14):1404-10

  Proton pump inhibitors exert anti-inflammatory effects and decrease human microglial and monocytic
   THP-1 cell neurotoxicity Hashioka S,Klegeris A,McGeer PL.pNeurol. 2009 May;217(1):177-83

18回伊勢神経懇話会:2009715()
症例報告C5-7頚椎症由来の自律神経障害によるAchen-Bach症候群.
  演者:宮崎眞佐男 座長:加藤保司。使用文献
 永田貴久、木藤正人 Achen-Bach症候群の3例皮膚科の臨床 481567-1570, 2006
症例報告:パーキンソン病のCamptocormia(腰曲がり)の治療。演者:加藤保司。座長:宮崎眞佐男 
   1)Neurology65; 355-359, 2005
   2)Nat Clin Pract Neurol . 2007 Sep;3(9):526-30
   3)Parkinsonism and related Disord 12 ;372-375,2006
症例:脳下垂体microadenoma由来の間脳・下垂体機能異常による過敏性腸症候群.
  演者:宮崎眞佐男。座長:小野直見。使用文献
   1)Efficacy of antidepressants and psychological therapies in irritable bowel  syndrome :systematic
  review and meta-analysis.Ford  AC, Talley NJ, Schoenfeld PS,Quigley EM, Moayyedi P. Gut.2009
  Mar;58(3):367-78.

  2)過敏性腸症候群Irritable bowel syndrome. Brandt  LJ, et al. Am J Gastroenterol.
  2009;104(suppl 1):S1-S34.

17回伊勢神経懇話会:2009624日(水)
症例報告:失立発作1例.演者:宮崎眞佐男。座長:小野直見
   日本神経学会てんかん治療ガイドライン.てんかん発作の国際分類(ILAE1981
   てんかんおよびてんかん症候群の新しい国際分類(ILAE1989
症例報告:神経調節性失神症候群・排尿後失神1例.演者:宮崎眞佐男 座長:加藤保司。   
  循環器病の診断と治療に関するガイドライン(2005-2006年度)失神の診断・治療ガイドライン
  Guidelines for Diagnosis and Treatment of Syncope(JCS2007) Circulation Journal Vol.71,Suppl.,2007
症例報告:
右内頸動脈・右視神経枝(cilliary artery)TIA.演者:加藤保司。座長:宮崎眞佐男
  Lampl Y,Boaz M,Gilad R,Lorberboym M et al. Neurology.2007 Oct 2;69(14):1404-10
   Laskowitz DT,et.al;BRAIN Study Group. Stroke.2009 Jan;40(1):77-85.,

16回伊勢神経懇話会:2009年5月27日(水)
症例報告:顔面チックⅠ型(精神的因子によるチック)と左顔面けいれん(Hemifacial spasm)  
  演者:宮崎眞佐男 座長:加藤保司。使用文献
  1) Parkinsonism Ralet Disord 2005 ;11:241-245
  2)小林武夫編 顔面筋の異状運動 片側顔面痙攣と病的共同運動の臨床2002 
  3)目崎高広, 龍兒ジストニアとボツリヌス治療 改訂第2,診断と治療社2005
症例報告:シンナー使用による若年性脳梗塞。
  演者:加藤保司。座長:宮崎眞佐男。使用文献
  1)Toxicol Ind Health.1995;11:253-307
  2)Arch Dis Child.1984;59:675-7
  3)Arch Environ Health.1999;54:231-41

15回伊勢神経懇話会:2009415日(水)
症例報告:臨床症状を持たない左側頭葉髄膜腫の1例.演者:宮崎眞佐男 座長:加藤保司。
  Indications for surgency in patients with asymptomatic meningiomas based on an extensive experience
  J Neurosurg 2006;105;538-543

症例報告:無症候性左中大脳動脈瘤の1例.演者:加藤保司。座長:宮崎眞佐男
  The international study of unruptured intracranial aneurysms investigation New Eng J      
   Med339:1725-1733.1998


14回伊勢神経懇話会:2009318()
症例報告:陳旧性多発神経炎(抗SSA抗体症候群)の1例。
  演者:宮崎眞佐男 座長:加藤保司。使用文献
  1Knabl JWitschi RHosl KReinold H et alNature2008  Jan 17451(7176)
  330-4
..
  2) JannMWSlade  JH Pharmcotherapy2007 Nov2711):1571-87
  3)村井克昌,宮崎眞佐男ら、Parkinson病の冷刺激による痛覚認知時間の延長について。
  神経内科.
6379-822005
  4)加藤総夫.慢性痛における扁桃体シナプス伝達の可逆的変化.
  医学のあゆみ
223:706-7122007
  5)南雅文,佐藤公道.「痛み」による「負の情動反応」における扁桃体の役割.
  日本薬理学雑誌 
1255-92005
  6)山口創.皮膚感覚の不思議.Blue backs.講談社
  7)日本医師会.日本医師会雑誌特別号 第119巻第12号。痩痛コントロールABC1998
  8)May A. Chronic pain may change the structure of brain. 2008 Jul;137(1):7-15
  9)Singer T, et al. Empathy for pain involves the affective but not sensory  components of pain.
    Science.2004;303:1157-62

  10)Eisenberger NI,et al.Dose rejection? An FNRI study of social exclusion.Science.2003;302:290-2.
症例報告:慢性甲状腺炎による甲状腺眼症(dysthyroid ocular myopathy
  演者:加藤保司。座長:宮崎眞佐男。使用文献
  1) Ruurd F Duyff,Joan Van den Bosch,D Martin Laman,Berr-Jan Potter van Loom,Wim H J P
  Linssen J Neurol Neurosurge Pyschiatry 2000;68:750-755

  2Bartelena L. et al. Management of GravesOphthalmopathy:Reality and Perspective.
  Endocrine Reviews. 21:168-199.2000.

  3)Bradley EA: Graves ophthalmopathy. Cuurent opinion of Ophthalmology 12:347-351,2001.
症例報告:多発性脳神経炎の1例。演者:宮崎眞佐男。座長:小野直見
 Keane JR.Arch Neurol.2005 Nov;62(11):1714-7.

13回伊勢神経懇話会:2009218日(水)
症例報告:右三叉神経炎1例。演者:宮崎眞佐男 座長:加藤保司。
  New Eng J Med339:1725-1733.1998.②端和夫.Jpn J Neurosurg 11.441-445,2002.
  ③脳卒中の外科
29:160-165,2001.③長峰義秀ら 脳卒中の外科 29:166-171,2001
症例報告:脳下垂体microadenomaによる間脳・下垂体機能異常1例。
  演者:加藤保司。座長:宮崎眞佐男。使用文献
  Brandt LJ,et al.Am J Gastroenterol.2009;104(suppl 1):S1-S34.
  
河野美幸ら、周期性嘔吐症 小児外科374Page4134182005.04
  ③花田卓也ら、周期性嘔吐症 小児科459Page1593-15972004.08
  ④橋本健一ら、片頭痛および母系にその家族歴を有し、
ACTHADH分泌異常を伴う成人発症
  周期性嘔吐症の1例
. 日本内分泌学会雑誌81Suppl.Page77-802005.06
  ShimizuTadashi,et al.A Case of Diabetes Mellitus Associated with Mitochondrial
  DNAMutation(3243A-G),Developed in Anorexia.PeriodicVomiting and Low Back Pain.Clinical
  Pediatric Endocrinology11:Suppl.17Page69-71(2001.11)

症例報告:てんかん性片側頭痛Hemicrania epileptica1例。
  演者:宮崎眞佐男。座長:小野直見。使用文献
     Mathew NT,et.al.Intravenous Valporate Sodium aborts Migraine rapidly. Headache.40:720-723,2000.
   ②国際頭痛分類第22004ICHD-Ⅱ)
症例検討:市立伊勢総合病院 問題症例
      (主訴)意識障害、痙攣?(現病歴)躁うつ病
    (神経学的所見)①意識障害JCS3
            ②過換気が強いときに右側臥位で左上下肢を宙に浮かし、間代性に不随意運動             あり→他者が強制的に制止することは可能で、
筋トーヌスも正.テタニー様手位もなし.
 (問題点)意識障害、低Na血症、多尿、過換気症候群、高CK血症、悪性症候群の合併はあるのか?

12回伊勢神経懇話会:2009121日(水)
症例報告:クレチン病(先天性甲状腺機能症)による症候性てんかんの1例。
  演者:宮崎眞佐男 座長:加藤保司。使用文献
  Lancet.2004 Dec 18-31;364(9452):2212-9.Cardiac arrhythmias in focal epilepsy:
  a prospective long-term study.

症例報告:健忘型軽度認知障害の1例。演者:加藤保司。座長:宮崎眞佐男
  Arch Genp Psychiatry. 2006 Jan;63(1):57-62.Use of Hippocampal and Amygdalar Volumes on
  Magnetic Resonance   Imaging to Predict Dementia in Cognitively Intact Elderly People.

症例報告:レビー小体型痴呆疑いの1例。演者:宮崎眞佐男。座長:小野直見
  Am J Geriatr Psychiatry.2007 Nov;15(11):961-7.Classification of psychotic symptoms in dementia
  with lewy bodies.

10回伊勢神経懇話会20081015
症例報告原因不明の味覚障害1例。演者:宮崎眞佐男。座長:小野直見
  1)Yasumatsu K,Katsukawa H,Sasamoto K et al :Recovery of amiloride-sensitive neural coding during
  regeneration of the gustatory nerve:behavioral-neural correlation of salt taste discrimination.
  J Neurosci 23:4362-8,2003.

  2)吉井清哲、大坪義孝、熊沢隆味蕾細胞間情報伝達生体の科学 56859,2005.
  3)安松啓子、三浦裕仁、吉田竜介ら:味を感じる:神経メカニズム.細胞工学 21142933,2002.
  4)Shoenfeld MA, Neuer G, Tempelmann C,Schussler K et sl :Functional magnetic resonance tomography
  correlates of taste perception in the human primary taste cortex. Neuroscience 127:347-53, 2004.

  5)野田昌作脳梗塞による味覚障害にparoxetineが有効であった1症例 
 神経治療学 
235057,2006.
  6)竹内誠ら:味覚障害のみで発症した橋梗塞の1例.脳と神経 5810057,2006.
  7)遠山潤ら:意識障害で発症し、顔面、下肢の感覚障害と味覚障害を呈した両側性傍正中視床梗塞
 の1小児例.脳と発達 
36659,2004.
  8)今村明子ら:味覚障害で発症した被殻出血.臨床神経 427503,2002.
症例報告:大脳基底核石灰化症(動脈硬化性) 1例。演者:加藤保司。座長:宮崎眞佐男
  1)Singh G,Sachdev MS,Tirath A,Gupta AK,Avasthi G. Focal cortical-subcortical
  calcifications(FCSCs)and epilepsy in the Indian subcontinent. Epilepsia.2000 Jun;41(6):718-26.
    2)D Lopez-Villegas,J Kulisevsky,J Deus,et al. Neuropsychological Alterations in Patients With Computed          Tomography-Detected Basal Ganglia Calcification. Arch Neurol.1996;53:251-6.
症例報告:
Double crash syndrome(手根管症候群+C5/6頸椎症) 1例。
 演者:宮崎眞佐男。座長:小野直見。使用文献
  1)S M Wong,A C F Hui,A Tang,P C Ho,L K Hung,K S Wong,R Kay,E Li. Local vs systemic corticosteroids
  in the treatment of carpal tunnel syndrome. Neurology.2001;56:1565-7.

   2)Ebenbichler GR,Resch KL,Nicolakis P,Wiesinger GF,Uhl F,et al. Ultrasound treatment for treating the
  carpal tunnel syndrome: randomized”sham”controlled trial. BMJ.1998 Mar 7;316(7133):731-5.

9回伊勢神経懇話会:2008年9月17日(水)
症例報告small fiber sensory neuropathy1例。 演者:宮崎眞佐男 座長:加藤保司。
  使用文献
 1)線維筋痛症候群(fibromyalgia syndrome
   2)Smallfiber sensory neuropathy(Small fiber neuropathy)
症例報告:ウイルス性脳幹脳炎による髄膜神経根炎の1例。演者:加藤保司。座長:宮崎眞佐男
 使用文献
  1) Pilot age and expertise predict flight simulator performance: a 3-year longitudinal study.
  Taylor JL, Kennedy Q, Noda A, Yesavage JA.Neurology.2007Feb27;68(9):648-54.

症例報告Trousseaus syndrome1例。演者:宮崎眞佐男。座長:小野直見
  使用文献
  1) The cortical involvement of territorial infarcts as a risk factor for stroke -related seizures.
  De Reuck J, De Groote L, Van Maele G, Proot P. Cerebrovasc Dis.2008;25(1-2):100-6.

  2) Trousseau’s(トルソー) syndrome(Stroke 2006;37:1155.神経内科58:463-467,2003.臨床神経学 
 42:227-232,2002.)

7回伊勢神経懇話会:2008618日(水)
症例報告:胸髄髄膜外脂肪腫(Angiolipoma1例。演者:加藤保司。座長:宮崎眞佐男
  使用文献
  村上忠誌ら、脊椎脊髄ジャーナル 19155158,2006. ②秋山尚子、臨床神経学39
  634638,1999.3)③飯島祐紀ら、臨床整形外科 38941944,2003.④津坂和文、田代邦雄. 
 脊椎脊髄 
13925929,2000.⑤宝田勝憲、大阪市医学会雑誌 36565586,1987.
症例報告:パーキンソン病によるCamptocormia1例。演者:宮崎眞佐男。座長:小野直見
  使用文献
  Azher SN,Jankovic J.Camptocormia:pathogenesis,classification,and response to therapy . Neurology.
  2005 Aug 9;65(3):355-9.

症例報告:Infantile Hemiplegiaによるてんかん性失語(Landau-Kleffner症候群)
  演者:宮崎眞佐男 座長:加藤保司。 
 使用文献

  de Veber G,Andrew M,Adams C,Bjornson B,Booth F,Buckley DJ,et.al.Cerebral sinovenous thrombosis
  in children.N Engl J Med.2001 Aug 9;345(6):417-23

 
6回伊勢神経懇話会:2008521日(水)
症例報告:自律神経発作1例。演者:宮崎眞佐男。座長:小野直見
  使用文献
  1)日本神経学会てんかん治療ガイドライン。てんかん発作の国際分類(ILAE1981)
  2)てんかんおよびてんかん症候群の新しい国際分類(ILAE1989)と本邦における頻度
症例報告:脳梁発育不全による精神薄弱とてんかん1例。演者:加藤保司。座長:宮崎眞佐男
  使用文献
  1) Corpus callosum in patients with obsessive-compulsive disorder:diffusion-tensor imaging study. Saito Y,   
  Nobuhara K,
 Okugawa G, Takase K, et al. Radiology. 2008Feb; 246(2): 536-42.

5回伊勢神経懇話会:2008416日(水)
症例報告:運動野の新鮮ラクネ梗塞での最新治療。演者:宮崎眞佐男 座長:加藤保司
  使用文献
  1)大脳皮質梗塞による限局性運動麻痺 神経内科 62(3):216-245,2005
症例報告:ウイルス性筋炎1例。演者:加藤保司。座長:宮崎眞佐男
  使用文献
  1)Neurol 30:877,80.Pediarics 57:255,76.Arch Neurol 29:441,732)内科 28:407.1971
  3)Ann Neurol 17:215,1985 神内 48:274,984)神内 7:312,1977 内科 53:457,1984
症例報告:一過性全健忘1例。演者:宮崎眞佐男。座長:小野直見
  使用文献
  1)Sedlaczek O,Hirsch JG, Grips E, Peters CN, et al. Neurology.2004 Jun22;62(12):2165-70

4回伊勢神経懇話会:2008326日(水)
症例報告:TNAs(Transient neurological attacks) 1例。演者:宮崎眞佐男。座長:小野直見
 使用文献
  1)Bos MJ,van Rijn MJ,Witteman JC,Hofman A,et al. Incidence and prognosis of transient
           neurological attacks.
JAMA .2007Des 26 ;298(24):2877-85.
症例報告:アルツハイマー型痴呆(臨床的特徴)。演者:宮崎眞佐男 座長:加藤保司
 使用文献
  R.J.Howard and others.Donepezil for the Treatment of Agitation in Alzheimer’s Disease.N Engl
  J Med.2007;357:1382-92.

症例報告:左橋ラクネ梗塞による右外転麻痺1例。演者:加藤保司。座長:宮崎眞佐男
 使用文献
 de Veber G,Andrew M,Adams C,Bjornson B,Booth F,Buckley DJ,et al.Cerebral sinovenous
 thrombosis in children.N Engl J Med.2001Aug9;345(6):417-23. 
 Laryngoscope 88:787-801,1978.Ann N Y Acad Sci 956:306-13,2002 ④Rev Neurol(Paris)  
 
137:393-413,1981.
Ann Neurol 40:928-32,1996.J Emerg Med 18:177-9,2000.
  Clin orthop 386:131-8,2001.J Med Virol 21:207-16,1987.⑨臨神 39:465-467,1999.⑩臨神  
 
36:358-361,1996.
Zh Nevropatol Psikhiatr Im S S Korsakova 81:43-7,1981. J Neurol Sci
 28:115-20,1976.
Dtsch Med Wochenschr 109:1160-4,1984. Rev Neurol(Paris) 140:665-8,1984.

3回伊勢神経懇話会:2008年2月14日(木)
症例報告:ラクネ状態→restless leg syndrome様病態1例。演者:宮崎眞佐男 座長:加藤保司
 使用文献
  1)Hogl B, Kiechl S, Willeit J, Saletu M, Frauscher B,Seppi K, Muller J,Rungger G, Gasperi A, Wenning G,
  Poewe W.  Restless leg syndrome
a community-based study of prevalence, severity, and risk factors.  
  Neurology.2005
 Jun1464(11)19204
症例:透明中隔嚢胞+ベルガ腔1例。演者:加藤保司。座長:宮崎眞佐男
 使用文献
  1)信州医学雑誌304544601982
  2)厚生省精神・神経疾患研究7年度研究報告書Page171-178,1996.03
  3)Wang KC, et al. Cephalalgia.200424867-74.
  4)秋久長夫ら.精神医学47399-4032005.
  5)Nakajima Y et al. Brain & development 8505-508,1986
症例報告:甲状腺機能低下症1例。演者:宮崎眞佐男。座長:小野直見
  使用文献:
  1)Roberts LM, Pattison H,Roalfe A, Franklyn J, Wilson S, et al.
  2) Is subclinical thyroid dysfunction in the elderly associated with depression or cognitive dysfunction? 
  Ann Intern Med 2006 Oct 17
145(8)573-81.

第2回伊勢神経懇話会:2008131日(木)
症例報告:血管性うつ状態1演者:宮崎眞佐男 座長:加藤保司
 使用文献
  1)Yasuma T,Saito S,Kihara K.Acta Pathologica Japonica 38:723,1988
  2)原田博文,泊一秀、若年者の腰椎MRI像の検討。整形外科と災害外科39 :436-440,1990
症例報告:血管性仮性パーキンソニズム1例。演者:加藤保司。座長:宮崎眞佐男
 使用文献
  1)Rascol O,Clanet M,Montastruc JL, et al:Abnormal ocular movements in Parkinson’s disease.
  Evidence for involvement of dopaminergic systems.Brain 1989;112:1193-1214

  2)Sharpe JA, Fletcher WA, Lang AE,et al:Smooth pursuit during dose-related on-off fluctuations in
  Parkinson’s disease.Neurology 1987;37:1389-1392

  3)川田憲一,宮崎眞佐男ら.パーキンソン病患者における発後の寡動と発話時音程の平坦化.
  臨床神経学44:703-706,2004.
  4)Goberman AM Coelho C:Acoustic analysis of parkinsonian speech Ⅰ、Ⅱ:speech characteristics and
  L-Dopa therapy. Neuro Rehabilitation 2002;17:237-246.2002;247-254.

  5)Gamboa J, Jimenez-Jimenez FJ,Nieto A, et al:Acoustic voice analysis in patients with Parkinson’s
  disease treated with dopaminergic drugs.J Voice 1997;11:314-320

症例報告:精神的発汗1例。演者:宮崎眞佐男。座長:小野直見
  使用文献
  1)間野忠明:ヒトの交換神経活動とその病態-Microneurographyによる研究- 自律神経303,  
   
215/222(1993)

  2)小川徳雄:発汗と自律神経学,医学のあゆみ32417/422(1976)
  3)小川徳雄:中枢発現機序と体液性要因、皮膚電気活動(新美良純ほか編),73/104 星和書店(1986)
  4)Iwase,S.et al.:Relationship among skin sympathetic nerveactivity,sweating and skin blood flow.Environmental        Medicine 32,55(1988)

  5)稲光哲明:心理面から見た手掌多汗症の診断と治療、発汗学10-125/29(2003)
  6)McWilliamset al.Br J Dermatol 117, 617/626,1987
  7)岩瀬 敏ほか:皮膚交感神経活動と発汗、神経内科 44-2, 121/130(1996)

1回伊勢神経懇話会:20071023日(火)             
症例報告:REM睡眠行動障害の2例.演者:宮崎眞佐男 座長:加藤保司 
  使用文献       
  Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative
  disorder:adescriptive study. Lancet Neurol.2006Jul;5(7):572-7.       

症例報告:破傷風不全型の1例.演者:加藤保司 座長:宮崎眞佐男
  使用文献
 脳と神経 55:973-9762003.②臨床神経学 45506-5092005.③破傷風(Tetanus)   「改定・感染症マニュアル」、厚生省保健医療局結核感染症課監修、マイガイア、1999